Literature DB >> 4147966

Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.

H Uehleke, K H Hellmer, S Tabarelli-Poplawski.   

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Year:  1973        PMID： 4147966     DOI： 10.1007/bf00502066

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


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  33 in total

1.  TRIFLUOROACETIC ACID AS METABOLITE OF HALOTHANE.

Authors:  A STIER
Journal:  Biochem Pharmacol       Date:  1964-11       Impact factor: 5.858

Review 2.  Halothane and the liver: a review of the epidemiologic, immunologic and metabolic aspects of the relationship.

Authors:  M H Dykes; J P Gilbert; P H Schur; E N Cohen
Journal:  Can J Surg       Date:  1972-07       Impact factor: 2.089

3.  [Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].

Authors:  O Reiner; S Athanassopoulos; K H Hellmer; R E Murray; H Uehleke
Journal:  Arch Toxikol       Date:  1972

4.  Metabolism of halogenated anesthetic agents as a possible cause of acneiform eruptions.

Authors:  L E Soper; T S Vitez; D Weinberg
Journal:  Anesth Analg       Date:  1973 Jan-Feb       Impact factor: 5.108

5.  Halothane: hepatitis or allergy?

Authors: 
Journal:  Lancet       Date:  1969-05-10       Impact factor: 79.321

6.  Antimitochondrial antibodies in jaundice following drug administration.

Authors:  M Rodriguez; F Paronetto; F Schaffner; H Popper
Journal:  JAMA       Date:  1969-04-07       Impact factor: 56.272

7.  [Binding of carbon tetrachloride to reduced microsomal cytochrome P-450 and to heme].

Authors:  O Reiner; H Uehleke
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1971-08

8.  A possible mechanism of toxicity of trifluoroethanol and other halothane metabolites.

Authors:  M M Airaksinen; P H Rosenberg; T Tammisto
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1970

9.  Binding of 14 C-carbon tetrachloride to microsomal proteins in vitro and formation of CHC1 3 by reduced liver microsomes.

Authors:  H Uehleke; K H Hellmer; S Tabarelli
Journal:  Xenobiotica       Date:  1973-01       Impact factor: 1.908

10.  Formation and binding of carbanions by cytochrome P-450 of liver microsomes.

Authors:  V Ullrich; K H Schnabel
Journal:  Drug Metab Dispos       Date:  1973 Jan-Feb       Impact factor: 3.922
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  12 in total

1.  A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo.

Authors:  H Uehleke; T Werner
Journal:  Arch Toxicol       Date:  1975-12-18       Impact factor: 5.153

2.  The mechanism of halothane binding to microsomal cytochrome P450.

Authors:  D Mansuy; W Nastainczyk; V Ullrich
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

3.  Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro.

Authors:  H Uehleke; S Poplawski-Tabarelli
Journal:  Arch Toxicol       Date:  1977-08-09       Impact factor: 5.153

4.  The effects of halothane on hepatic microsomal electron transfer.

Authors:  M C Berman; K M Ivanetich; J E Kench
Journal:  Biochem J       Date:  1975-05       Impact factor: 3.857

5.  Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation.

Authors:  H Uehleke; S Tabarelli-Poplawski; G Bonse; D Henschler
Journal:  Arch Toxicol       Date:  1977-06-18       Impact factor: 5.153

6.  Effect of surgery under general anaesthesia on antipyrine clearance.

Authors:  D Pessayre; H Allemand; C Benoist; F Afifi; M François; J P Benhamou
Journal:  Br J Clin Pharmacol       Date:  1978-12       Impact factor: 4.335

7.  Characterization of a halothane-induced humoral immune response in rabbits.

Authors:  A H Callis; S D Brooks; T P Roth; A J Gandolfi; B R Brown
Journal:  Clin Exp Immunol       Date:  1987-02       Impact factor: 4.330

Review 8.  Clinical pharmacokinetics of the inhalational anaesthetics.

Authors:  O Dale; B R Brown
Journal:  Clin Pharmacokinet       Date:  1987-03       Impact factor: 6.447

9.  Chronology of halothane-induced antigen expression in halothane-exposed rabbits.

Authors:  T P Roth; A K Hubbard; A J Gandolfi; B R Brown
Journal:  Clin Exp Immunol       Date:  1988-05       Impact factor: 4.330

Review 10.  Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation.

Authors:  H Kappus; H Sies
Journal:  Experientia       Date:  1981-12-15
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