Literature DB >> 4147578

Induction of a primary antihapten response in vivo by a graft-vs.-host reaction.

J A Hamilton, J F Miller.   

Abstract

A primary anti-NIP PFC response can be elicited by a GVH reaction provided certain structural requirements of the NIP-carrier are met. NIP-coated F(1) erythrocytes and NIP-coated parental erythrocytes give rise to substantial anti-NIP PFC responses in F(1) mice after the injection of parental spleens. These conjugates do not of themselves give rise to an anti-NIP PFC response and, in fact, normally give rise to NIP-specific tolerance. In contrast the GVH reaction is not able to enhance the primary anti-NIP PFC response to immunogenic NIP-conjugates.

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Year:  1973        PMID： 4147578      PMCID： PMC2180566          DOI： 10.1084/jem.138.4.1009

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  7 in total

Review 1.  The allogeneic effect on immune responses: model for regulatory influences of T lymphocytes on the immune system.

Authors:  D H Katz
Journal:  Transplant Rev       Date:  1972

Review 2.  The regulatory influence of activated T cells on B cell responses to antigen.

Authors:  D H Katz; B Benacerraf
Journal:  Adv Immunol       Date:  1972       Impact factor: 3.543

3.  Cell-to-cell interaction in the immune response. VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory.

Authors:  J F Miller; J Sprent
Journal:  J Exp Med       Date:  1971-07-01       Impact factor: 14.307

4.  Further improvements in the plaque technique for detecting single antibody-forming cells.

Authors:  A J Cunningham; A Szenberg
Journal:  Immunology       Date:  1968-04       Impact factor: 7.397

5.  Chemical and serological studies with an iodine-containing synthetic immunological determinant 4-hydroxy-3-iodo-5-nitrophenylacetic acid (NIP) and related compounds.

Authors:  A Brownstone; N A Mitchison; R Pitt-Rivers
Journal:  Immunology       Date:  1966-05       Impact factor: 7.397

6.  The allogeneic effect in inbred mice. I. Experimental conditions for the enhancement of hapten-specific secondary antibody responses by the graft-versus-host reaction.

Authors:  D P Osborne; D H Katz
Journal:  J Exp Med       Date:  1972-09-01       Impact factor: 14.307

7.  The allogeneic effect in inbred mice. 3. Unique antigenic structural requirements in the expression of the phenomenon on unprimed cell populations in vivo.

Authors:  D P Osborne; D H Katz
Journal:  J Exp Med       Date:  1973-04-01       Impact factor: 14.307
  7 in total
  3 in total

1.  Injection of mouse thyroglobulin and/or adult thymectomy do not break tolerance to thyroglobulin during the lupus like graft versus host disease in mice.

Authors:  F M van Rappard-van der Veen; Y M Kong; N R Rose; M Kimura; E Gleichmann
Journal:  Clin Exp Immunol       Date:  1984-03       Impact factor: 4.330

2.  The influence of intracellular levels of cyclic nucleotides on cell proliferation and the induction of antibody synthesis.

Authors:  J Watson
Journal:  J Exp Med       Date:  1975-01-01       Impact factor: 14.307

3.  Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires.

Authors:  Martin Faderl; Fabian Klein; Oliver F Wirz; Stefan Heiler; Llucia Albertí-Servera; Corinne Engdahl; Jan Andersson; Antonius Rolink
Journal:  Front Immunol       Date:  2018-01-22       Impact factor: 7.561
  3 in total

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