Literature DB >> 4144545

Enzymatic oxidation of nicotine to nicotine 1'(5') iminium ion. A newly discovered intermediate in the metabolism of nicotine.

P J Murphy.   

Abstract

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Year:  1973        PMID： 4144545

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  17 in total

1.  Catalytic mechanism of cytochrome P450 for 5'-hydroxylation of nicotine: fundamental reaction pathways and stereoselectivity.

Authors:  Dongmei Li; Xiaoqin Huang; Keli Han; Chang-Guo Zhan
Journal:  J Am Chem Soc       Date:  2011-04-22       Impact factor: 15.419

2.  Fundamental reaction pathways for cytochrome P450-catalyzed 5'-hydroxylation and N-demethylation of nicotine.

Authors:  Dongmei Li; Yong Wang; Keli Han; Chang-Guo Zhan
Journal:  J Phys Chem B       Date:  2010-07-15       Impact factor: 2.991

Review 3.  Aspects of the oxidative metabolism of nicotine.

Authors:  G B Neurath
Journal:  Clin Investig       Date:  1994-02

4.  Not only smoking is deadly: fatal ingestion of e-juice-a case report.

Authors:  Svenja Bartschat; Katja Mercer-Chalmers-Bender; Justus Beike; Markus A Rothschild; Martin Jübner
Journal:  Int J Legal Med       Date:  2014-09-20       Impact factor: 2.686

5.  Metabolism of (-)-(S)-nicotine by guinea pig and rat brain: identification of cotinine.

Authors:  P Jacob; M Ulgen; J W Gorrod
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1997 Oct-Dec       Impact factor: 2.441

6.  Pharmacokinetics and metabolism of N-(2-hydroxyethyl)-2,5-[14C]-pyrrolidine (HEP, Epolamine) in male healthy volunteers.

Authors:  C Giachetti; A Assandri; G Mautone; E Tajana; B Palumbo; R Palumbo
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1996 Jul-Sep       Impact factor: 2.441

7.  Structural Analysis Provides Mechanistic Insight into Nicotine Oxidoreductase from Pseudomonas putida.

Authors:  Margarita A Tararina; Kim D Janda; Karen N Allen
Journal:  Biochemistry       Date:  2016-11-18       Impact factor: 3.162

8.  The metabolism of nicotine-delta 1'(5')-iminium ion, in vivo and in vitro.

Authors:  J W Gorrod; A R Hibberd
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1982 Oct-Dec       Impact factor: 2.441

9.  A physiologically based pharmacokinetic model for nicotine and cotinine in man.

Authors:  D E Robinson; N J Balter; S L Schwartz
Journal:  J Pharmacokinet Biopharm       Date:  1992-12

10.  Catalytic mechanism of cytochrome P450 for N-methylhydroxylation of nicotine: reaction pathways and regioselectivity of the enzymatic nicotine oxidation.

Authors:  Dongmei Li; Xiaoqin Huang; Jianping Lin; Chang-Guo Zhan
Journal:  Dalton Trans       Date:  2013-01-09       Impact factor: 4.390
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