Literature DB >> 414274

Acetylcholine antirelease effect of morphine and its modification by calcium.

G Sanfaçon, G Labrecque.   

Abstract

The effects of morphine (10 mg/kg) and calcium (10 mg/kg) were studied on the neocortical release of acetylcholine (ACh) in ketamine-anesthetized rats. Morphine decreased ACh release as measured by the dorsal leech muscle as well as by an enzymatic assay. Calcium was ineffective alone but antagonized the action of morphine. This study supports the hypothesis that the ACh antirelease action of narcotics is mediated through an interaction with calcium.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 414274     DOI： 10.1007/bf01457851

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  19 in total

1.  DEPRESSION BY MORPHINE AND CHLORALOSE OF ACETYLCHOLINE RELEASE FROM THE CAT'S BRAIN.

Authors:  D BELESLIN; R L POLAK
Journal:  J Physiol       Date:  1965-04       Impact factor: 5.182

2.  The effect of calcium ions on the motor end-plate potentials.

Authors:  J DEL CASTILLO; L STARK
Journal:  J Physiol       Date:  1952-04       Impact factor: 5.182

3.  Spontaneous subthreshold activity at motor nerve endings.

Authors:  P FATT; B KATZ
Journal:  J Physiol       Date:  1952-05       Impact factor: 5.182

Review 4.  Membrane phenomena.

Authors:  A Rothstein
Journal:  Annu Rev Physiol       Date:  1968       Impact factor: 19.318

5.  Tolerance to and physical dependence on morphine: relation to neocortical acetylcholine release in the cat.

Authors:  G Labrecque; E F Domino
Journal:  J Pharmacol Exp Ther       Date:  1974-10       Impact factor: 4.030

6.  Central release of acetylcholine following administration of morphine to unanesthetized rabbits.

Authors:  W J Mullin
Journal:  Can J Physiol Pharmacol       Date:  1974-06       Impact factor: 2.273

7.  Effects of morphine, nalorphine and naloxone on neocortical release of acetylcholine in the rat.

Authors:  J D Matthews; G Labrecque; E F Domino
Journal:  Psychopharmacologia       Date:  1973-03-16

8.  Stereospecific interaction of opiate narcotics in binding of 3H-dihydromorphine to membranes of rat brain.

Authors:  D T Wong; J S Horng
Journal:  Life Sci       Date:  1973-12-01       Impact factor: 5.037

9.  Changes of brain calcium content in normal and morphinized mice after the administration of morphine.

Authors:  T Shikimi; H Kaneto; K Hano
Journal:  Jpn J Pharmacol       Date:  1967-03

10.  The characteristics of acetylcholine release mechanisms in the auditory cortex.

Authors:  B A Hemsworth; J F Mitchell
Journal:  Br J Pharmacol       Date:  1969-05       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.