Literature DB >> 414273

6-Hydroxydopamine inhibits some effects of mescaline centrally administered to rabbits.

S Ferri, R A Reina, P Braga.   

Abstract

The narcotic antagonist naloxone does not antagonize antinociception elicited in the rabbit by 100 microgram/kg of mescaline centrally administered, whereas pretreatment with 6-hydroxydopamine (6-OHDA) inhibits this mescaline effect. Stereotyped behavior of rabbits following central mescaline administration is also prevented by 6-hda pretreatment. Since 6-OHDA in known to produce a degeneration of catecholamine containing nerve terminals, a crucial role of catecholamines is suggested in the complex of effects seen in the rabbit after central administration of the hallucinogen.

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Year:  1977        PMID： 414273     DOI： 10.1007/bf01457850

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  11 in total

1.  A permanent cannula for intraventricular injections in cats.

Authors:  W FELDBERG; S L SHERWOOD
Journal:  J Physiol       Date:  1953-04-28       Impact factor: 5.182

2.  Effect of 6-hydroxydopamine, 5,6-dihydroxytryptamine and raphe lesions on the antinociceptive actions of morphine in rats.

Authors:  J Bläsig; K Reinhold; A Herz
Journal:  Psychopharmacologia       Date:  1973-07-17

3.  Effect of chemical sympathectomy on morphine antinociception and tolerance development in the rat.

Authors:  H N Bhargava; A H Afifi; E L Way
Journal:  Biochem Pharmacol       Date:  1973-11-01       Impact factor: 5.858

4.  The effect of 6-hydroxydopamine on morphine tolerance and physical dependence.

Authors:  G Friedler; H N Bhargava; R Quock; E L Way
Journal:  J Pharmacol Exp Ther       Date:  1972-10       Impact factor: 4.030

5.  Effect of 6-hydroxydopamine on morphine analgesia.

Authors:  I H Ayhan
Journal:  Psychopharmacologia       Date:  1972

6.  Athetoid and choreiform hyperkinesias produced by caudate application of dopamine in cats.

Authors:  A R Cools
Journal:  Psychopharmacologia       Date:  1972

7.  Effect of 6-hydroxydopamine on brain norepinephrine and dopamine evidence for selective degeneration of catecholamine neurons.

Authors:  G R Breese; T D Traylor
Journal:  J Pharmacol Exp Ther       Date:  1970-09       Impact factor: 4.030

8.  Caudal dopamine and stereotype behaviour of cats.

Authors:  A R Cools; J M van Rossum
Journal:  Arch Int Pharmacodyn Ther       Date:  1970-09

9.  Effects of depletion of brain catecholamines during the development of morphine dependence on precipitated withdrawal in rats.

Authors:  J Bläsig; A Herz; C Gramsch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

10.  Development of tolerance to the antinociceptive effect of mescaline intraventricularly administered to rabbits.

Authors:  S Ferri; A Santagostino; P C Braga
Journal:  Psychopharmacology (Berl)       Date:  1976-06-23       Impact factor: 4.530
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  2 in total

1.  Possible mediation of catecholaminergic pathways in the antinociceptive effect of an extract of Cannabis sativa L.

Authors:  S Ferri; E Cavicchini; P Romualdi; E Speroni; G Murari
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

2.  Investigations on behavioral effects of an extract of Cannabis sativa L. in the rat.

Authors:  S Ferri; G Costa; G Murari; A M Panico; E Rapisarda; E Speroni; R Arrigo-Reina
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530
  2 in total

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