Literature DB >> 4135820

Lymphocyte sensitization to basic protein of brain in multiple sclerosis and other neurological diseases.

E A Caspary, E J Field.   

Abstract

The number of lymphocytes in the blood sensitized to encephalitogenic factor (EF) is less in multiple sclerosis than it is in general paralysis of the insane. The number appears related to the extent of parenchymatous destruction. The study offers no support for the view that lymphocyte sensitization to EF is of pathogenetic significance in multiple sclerosis.

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Year:  1974        PMID： 4135820      PMCID： PMC494749          DOI： 10.1136/jnnp.37.6.701

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  8 in total

1.  AN ENCEPHALITOGENIC PROTEIN OF HUMAN ORIGIN: SOME CHEMICAL AND BIOLOGICAL PROPERTIES.

Authors:  E A CASPARY; E J FIELD
Journal:  Ann N Y Acad Sci       Date:  1965-03-31       Impact factor: 5.691

2.  The macrophage electrophoretic migration (MEM) test for lymphocyte sensitization. A study of the kinetics.

Authors:  P R Carnegie; E A Caspary; J P Dickinson; E J Field
Journal:  Clin Exp Immunol       Date:  1973-05       Impact factor: 4.330

3.  Lymphocyte transformation in vitro measured by tritiated thymidine uptake. I. Lymphocyte culture techniques.

Authors:  D Hughes; E A Caspary
Journal:  Int Arch Allergy Appl Immunol       Date:  1970

4.  Sensitization of blood lymphocytes to possible antigens in neurological disease.

Authors:  E A Caspary; E J Field
Journal:  Eur Neurol       Date:  1970       Impact factor: 1.710

5.  Demonstration of sensitized lymphocytes in blood.

Authors:  E J Field; E A Caspary
Journal:  J Clin Pathol       Date:  1971-03       Impact factor: 3.411

6.  Lymphocyte sensitisation: an in-vitro test for cancer?

Authors:  E J Field; E A Caspary
Journal:  Lancet       Date:  1970-12-26       Impact factor: 79.321

7.  Response of human blood lymphocytes to tuberculin PPD in tissue culture.

Authors:  A S Coulson; D G Chalmers
Journal:  Immunology       Date:  1967-04       Impact factor: 7.397

8.  Specific lymphocyte sensitization in cancer: is there a common antigen in human malignant neoplasia?

Authors:  E A Caspary; E J Field
Journal:  Br Med J       Date:  1971-06-12
  8 in total
  2 in total

1.  Scrapie: a review of its relation to human disease and ageing.

Authors:  E J Field
Journal:  J Med Genet       Date:  1976-12       Impact factor: 6.318

2.  Biochemical findings in multiple sclerosis. V. Transformation of lymphocytes from patients with multiple sclerosis by human basic protein.

Authors:  F Gosseye-Lissoir; P Delmotte; H Carton
Journal:  J Neurol       Date:  1977-10-07       Impact factor: 4.849
  2 in total

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