Literature DB >> 413496

Toxicity and persistence of low-level PCB in adult wistar rats, fetuses, and young.

F D Baker, B Bush, C F Tumasonis, F C Lo.   

Abstract

Aroclor 1254 was fed to female and male rats daily for 9 weeks at a dose of 6.4 mg/kg in their drinking water. Control animals received plain tap water plus the emulsified (0.15% Tween 80). Elevated mixed function oxidase (MFO) activity appeared to be due to 2,4,5,2',4',5'- and 2,4,5,2'3'4'-hexachlorobiphenyls, since only these compounds were present to any degree in the tissues of the animals when MFO activity persisted after termination of exposure. The placenta apparently is an effective barrier to PCB transfer.

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Year:  1977        PMID： 413496     DOI： 10.1007/bf02220897

Source DB:  PubMed          Journal:  Arch Environ Contam Toxicol        ISSN： 0090-4341            Impact factor:   2.804


  19 in total

1.  THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE.

Authors:  T OMURA; R SATO
Journal:  J Biol Chem       Date:  1964-07       Impact factor: 5.157

2.  Polychlorinated biphenyls: hydroxylated urinary metabolites of 2,5,2',5'-tetrachlorobiphenyl identified in rabbits.

Authors:  A M Gardner; J T Chen; J A Roach; E P Ragelis
Journal:  Biochem Biophys Res Commun       Date:  1973-12-19       Impact factor: 3.575

3.  Thin-layer chromatography for quantitative polychlorinated biphenyl analysis.

Authors:  B Bush; F C Lo
Journal:  J Chromatogr       Date:  1973-03-28

4.  Arene oxides and the NIH shift: the metabolism, toxicity and carcinogenicity of aromatic compounds.

Authors:  J W Daly; D M Jerina; B Witkop
Journal:  Experientia       Date:  1972-10-15

5.  Polychlorinated biphenyls: evidence of transplacental passage in the Sherman rat.

Authors:  A Curley; V W Burse; M E Grim
Journal:  Food Cosmet Toxicol       Date:  1973-06

6.  Effects and interactions of environmental chemicals on human cells in tissue culture.

Authors:  C L Litterst; E P Lichtenstein
Journal:  Arch Environ Health       Date:  1971-04

7.  Effect of two isomeric tetrachlorobiphenyls on rats and their hepatic enzymes.

Authors:  P R Chen; H M Mehendale; L Fishbein
Journal:  Arch Environ Contam Toxicol       Date:  1973-02       Impact factor: 2.804

8.  Interpretation of persistence and effects of polychlorinated biphenyls in birds.

Authors:  S Bailey; P J Bunyan
Journal:  Nature       Date:  1972-03-03       Impact factor: 49.962

9.  Polychlorinated biphenyls as inducers of hepatic porphyria in Japanese quail, with special reference to -aminolevulinic acid synthetase activity, fluorescence, and residues in the liver.

Authors:  J G Vos; J J Strik; C W van Holsteÿn; J H Pennings
Journal:  Toxicol Appl Pharmacol       Date:  1971-10       Impact factor: 4.219

10.  Polychlorobiphenyls (PCB) induced fetopathy. II. Experimental studies: possible placental transfer of polychlorobiphenyls in rats.

Authors:  T Kato; M Yakushiji; H Tsuda; A Arima; K Takahashi
Journal:  Kurume Med J       Date:  1972
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  7 in total

1.  Precipitation of 78 PCB congeners from aqueous solution by clay.

Authors:  B Bush; L Shane; L Wood
Journal:  Bull Environ Contam Toxicol       Date:  1990-07       Impact factor: 2.151

2.  A congener analysis of polychlorinated biphenyls accumulating in rat pups after perinatal exposure.

Authors:  W Shain; S R Overmann; L R Wilson; J Kostas; B Bush
Journal:  Arch Environ Contam Toxicol       Date:  1986-11       Impact factor: 2.804

3.  Chronic toxicity studies of crude organic chemical pollutants, illustrated by studies with Aroclor 1254.

Authors:  B Bush; F C Lo; F D Baker; C F Tumasonis; G Therriault; M Zdeb
Journal:  Arch Environ Contam Toxicol       Date:  1983-03       Impact factor: 2.804

Review 4.  Placenta Disrupted: Endocrine Disrupting Chemicals and Pregnancy.

Authors:  Jeremy Gingrich; Elvis Ticiani; Almudena Veiga-Lopez
Journal:  Trends Endocrinol Metab       Date:  2020-04-02       Impact factor: 12.015

5.  Polychlorobiphenyl (PCB) congeners, p,p'-DDE, and hexachlorobenzene in maternal and fetal cord blood from mothers in Upstate New York.

Authors:  B Bush; J Snow; R Koblintz
Journal:  Arch Environ Contam Toxicol       Date:  1984-09       Impact factor: 2.804

6.  Accumulation and persistence of individual polychlorinated biphenyl congeners in liver, blood, and adipose tissue of rats following dietary exposure to Aroclor 1254.

Authors:  R W Nims; S D Fox; H J Issaq; R A Lubet
Journal:  Arch Environ Contam Toxicol       Date:  1994-11       Impact factor: 2.804

7.  Altered biologic activities of commercial polychlorinated biphenyl mixtures after microbial reductive dechlorination.

Authors:  M A Mousa; P E Ganey; J F Quensen; B V Madhukar; K Chou; J P Giesy; L J Fischer; S A Boyd
Journal:  Environ Health Perspect       Date:  1998-12       Impact factor: 9.031
  7 in total

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