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Literature DB >> 4134465

Isolation and characterization of RNA-directed DNA polymerase from a B-type RNA tumor virus.

A S Dion, B Vaidya, G S Fout, D H Moore.

Abstract

RNA-directed DNA polymerase was isolated from milk-borne B-type murine mammary tumor virus of the RIII mouse strain. The several hundred-fold-purified enzyme sediments at 5.5 to 5.7S with an average molecular weight of approximately 100,000. The purified enzyme is completely template dependent and responds to RNA, DNA, and synthetic templates. Stability studies indicate differential lability dependent on the exogenous template used to monitor activity.

Entities: Disease Species

Mesh：

Substances：

Year: 1974 PMID： 4134465 PMCID： PMC355475

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

18 in total

1. RNA-dependent DNA polymerase activity of RNA tumor viruses. I. Directing influence of DNA in the reaction.

Authors: J Hurwitz; J P Leis
Journal: J Virol Date: 1972-01 Impact factor: 5.103

2. Purification of the DNA polymerase of avian myeloblastosis virus.

Authors: D L Kacian; K F Watson; A Burny; S Spiegelman
Journal: Biochim Biophys Acta Date: 1971-09-24

3. Purification and characterization of the deoxyribonucleic acid polymerase associated with Rous sarcoma virus.

Authors: A J Faras; J M Taylor; J P McDonnell; W E Levinson; J M Bishop
Journal: Biochemistry Date: 1972-06-06 Impact factor: 3.162

4. Simultaneous detection of reverse transcriptase and high molecular weight RNA unique to oncogenic RNA viruses.

Authors: J Schlom; S Spiegelman
Journal: Science Date: 1971-11-19 Impact factor: 47.728

5. Properties of a soluble DNA polymerase isolated from Rous sarcoma virus.

Authors: P Duesberg; K V Helm; E Canaani
Journal: Proc Natl Acad Sci U S A Date: 1971-04 Impact factor: 11.205

6. Gel electrophoresis of reverse transcriptase activity of murine mammary tumour virions.

Authors: A S Dion; D H Moore
Journal: Nat New Biol Date: 1972-11-01

7. Reverse transcriptases of primate viruses as immunological markers.

Authors: E M Scolnick; W P Parks; G J Todaro
Journal: Science Date: 1972-09-22 Impact factor: 47.728

8. Reverse transcriptase and high molecular weight RNA in particles from mouse and human milk.

Authors: J Schlom; S Spiegelman; D H Moore
Journal: J Natl Cancer Inst Date: 1972-04 Impact factor: 13.506

9. Separation of murine cellular and murine leukaemia virus DNA polymerases.

Authors: J Ross; E M Scolnick; G J Todaro; S A Aaronson
Journal: Nat New Biol Date: 1971-06-09

10. Serological analysis of the deoxyribonucleic acid polymerase of avian oncornaviruses. II. Comparison of avian deoxyribonucleic acid polymerases.

Authors: R C Nowinski; K F Watson; A Yaniv; S Spiegelman
Journal: J Virol Date: 1972-11 Impact factor: 5.103

7 in total

1. Electrophoretic analysis of the molecular weight of murine mammary tumor virus RNA.

Authors: A S Dion; U I Heine; A A Pomenti; J Korb; G H Weber
Journal: J Virol Date: 1977-06 Impact factor: 5.103

2. Structural components of mouse mammary tumor virus. II. Isolation and purification of virion polypeptides.

Authors: M J Yagi; R E Stutzman; B H Robertson; R W Compans
Journal: J Virol Date: 1978-05 Impact factor: 5.103

3. Reverse transcriptase of mouse mammary tumour virus: expression in bacteria, purification and biochemical characterization.

Authors: R Taube; S Loya; O Avidan; M Perach; A Hizi
Journal: Biochem J Date: 1998-02-01 Impact factor: 3.857

4. Murine intracisternal type A particles: a biochemical characterization.

Authors: F Wong-Staal; M S Reitz; C D Trainor; R C Gallo
Journal: J Virol Date: 1975-10 Impact factor: 5.103

5. RNA-dependent DNA polymerase of an endogenous type C virus of mice: purification and partial characterization.

Authors: A Hizi; A Yaniv
Journal: J Virol Date: 1980-06 Impact factor: 5.103

6. Murine mammary tumor virus pol-related sequences in human DNA: characterization and sequence comparison with the complete murine mammary tumor virus pol gene.

Authors: K C Deen; R W Sweet
Journal: J Virol Date: 1986-02 Impact factor: 5.103

7. RNase H and RNA-directed DNA polymerase: associated enzymatic activities of murine mammary tumor virus.

Authors: A S Dion; C J Williams; D H Moore
Journal: J Virol Date: 1977-04 Impact factor: 5.103

7 in total