Literature DB >> 4132653

Mobilization of gastric mucosal histamine and gastric secretion after H2-receptor blockade.

L Lundell.   

Abstract

The effects of two H(2)-receptor antagonists (burimamide and metiamide) on the mobilization of gastric mucosal histamine, as shown by its urinary excretion and acid secretion following pentagastrin infusion, were studied in rats provided with Heidenhain pouches. Pentagastrin-induced secretion was completely inhibited without major Alterations in urinary excretion of histamine. These observations can easily be reconciled with the hypothesis that pentagastrin is not a direct stimulant of the parictal cell.

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Year:  1973        PMID： 4132653      PMCID： PMC1776608          DOI： 10.1111/j.1476-5381.1973.tb08552.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  4 in total

1.  Preparation of chronic denervated gastric pouches in the rat.

Authors:  R S ALPHIN; T M LIN
Journal:  Am J Physiol       Date:  1959-08

2.  Definition and antagonism of histamine H 2 -receptors.

Authors:  J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal:  Nature       Date:  1972-04-21       Impact factor: 49.962

3.  The secretory pattern of three stomach preparations in the rat.

Authors:  S E Svensson
Journal:  J Physiol       Date:  1970-04       Impact factor: 5.182

4.  Gastric secretion and its facilitation as related to gastric mucosal histamine.

Authors:  I Johansson; L Lundell; E Rosengren; S E Svensson
Journal:  J Physiol       Date:  1972-10       Impact factor: 5.182
  4 in total
  7 in total

1.  Classification and biological distribution of histamine receptor sub-types.

Authors:  N Chand; P Eyre
Journal:  Agents Actions       Date:  1975-10

2.  Classification and biological distribution of histamine receptor sub-types. 1975.

Authors:  N Chand; P Eyre
Journal:  Agents Actions       Date:  1994-12

3.  Relations between the effects of histamine, pheniramin and metiamide on spontaneous motility and the formation of cyclic AMP in the isolated rat uterus.

Authors:  P Mitznegg; E Schubert; W Fuchs
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

4.  Histamine metabolism of the guinea-pig gastric mucosa.

Authors:  J Bergmark; G Granerus; S Henningsson; L Lundell; E Rosengren
Journal:  J Physiol       Date:  1976-05       Impact factor: 5.182

5.  Further studies on the mode of action of isoprenaline on gastric secretion in the conscious rat.

Authors:  L Lundell; S E Svensson; G Nilsson
Journal:  Br J Pharmacol       Date:  1976-09       Impact factor: 8.739

6.  Inhibition by metiamide of secretagogue-induced gastric acid secretion in the conscious Heidenhain pouch rat.

Authors:  K T Bunce; M E Parsons
Journal:  J Physiol       Date:  1978-12       Impact factor: 5.182

7.  Elicidation by a H-2-receptor antagonist of the significance of mucosal histamine mobilization in exciting acid secretion.

Authors:  L Lundell
Journal:  J Physiol       Date:  1975-01       Impact factor: 5.182
  7 in total

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