Literature DB >> 413150

Morphine and shuttle-box self-stimulation in the rat: a model for euphoria.

R A Levitt, J H Baltzer, T M Evers, D J Stilwell, J E Furby.   

Abstract

In a shuttle-box self-stimulation paradigm, analgesic doses of morphine increase the amount of time a rat leaves rewarding brain stimulation on, without altering average OFF times. This paradigm may serve as a model for the euphoria induced by narcotic drugs and as a useful tool for evaluating the reinforcing effects of drugs.

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Year:  1977        PMID: 413150     DOI: 10.1007/bf00426581

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  22 in total

Review 1.  PROBLEMS OF MEASUREMENT AND INTERPRETATION WITH REINFORCING BRAIN STIMULATION.

Authors:  E S VALENSTEIN
Journal:  Psychol Rev       Date:  1964-11       Impact factor: 8.934

2.  Effects of chlorpromazine, meprobamate, pentobarbital and morphine on self-stimulation.

Authors:  J OLDS; R P TRAVIS
Journal:  J Pharmacol Exp Ther       Date:  1960-04       Impact factor: 4.030

3.  Separation of inhibiting and stimulating effects of morphine on self-stimulation behaviour by intracerebral microinjections.

Authors:  C L Broekkamp; J H Van den Bogaard; H J Heijnen; R H Rops; A R Cools; J M Van Rossum
Journal:  Eur J Pharmacol       Date:  1976-04       Impact factor: 4.432

4.  Opioid peptides endorphins in pituitary and brain.

Authors:  A Goldstein
Journal:  Science       Date:  1976-09-17       Impact factor: 47.728

5.  Do rats terminate hypothalamic stimulation only in order to turn it on again?

Authors:  J Mendelson; W J Freed
Journal:  Behav Biol       Date:  1973-05

6.  Influence of morphine on lateral hypothalamic self-stimulation in the rat.

Authors:  S A Lorens; C L Mitchell
Journal:  Psychopharmacologia       Date:  1973-09-28

7.  Lateral hypothalamic stimulation: inhibition of aversive effects by feeding, drinking, and gnawing.

Authors:  J Mendelson
Journal:  Science       Date:  1969-12-12       Impact factor: 47.728

8.  Comparison of the effects of morphine on hypothalamic and medial frontal cortex self-stimulation in the rat.

Authors:  S A Lorens
Journal:  Psychopharmacology (Berl)       Date:  1976-07-28       Impact factor: 4.530

9.  Object-carrying by rats: an approach to the behavior produced by brain stimulation.

Authors:  A G Phillips; V C Cox; J W Kakolewski; E S Valenstein
Journal:  Science       Date:  1969-11-14       Impact factor: 47.728

10.  Analgesia mediated by a direct spinal action of narcotics.

Authors:  T L Yaksh; T A Rudy
Journal:  Science       Date:  1976-06-25       Impact factor: 47.728

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  1 in total

1.  Associative factors in the effects of morphine on self-stimulation.

Authors:  T H Hand; K B Franklin
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

  1 in total

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