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Literature DB >> 4127029

Studies on the nucleic acid sequences of Kirsten sarcoma virus: a model for formation of a mammalian RNA-containing sarcoma virus.

E M Scolnick, E Rands, D Williams, W P Parks.

Abstract

The genetic information contained in the Kirsten and Moloney strains of mammalian RNA-containing sarcoma viruses has been analyzed by RNA . (3)H-DNA hybridization. Kirsten sarcoma virus has been found to possess two distinct sets of nucleic acid sequences. One set of sequences is contained in murine type C helper virus, and the other set is contained in rat type C helper virus. Moloney sarcoma virus contains sequences of murine type C helper virus but not of rat type C helper virus. The results indicate that Kirsten sarcoma virus arose through a process of recombination between Kirsten murine leukemia virus and nucleic acid sequences found in rat cells. A model is suggested for the formation of transforming type C viruses involving the transduction of oncogenic information.

Entities: Disease Species

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Year: 1973 PMID： 4127029 PMCID： PMC356651

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

17 in total

1. Induction of mutations in an RNA tumour virus by an analogue of a DNA precursor.

Authors: J P Bader; N R Brown
Journal: Nat New Biol Date: 1971-11-03

2. Differences between the ribonucleic acids of transforming and nontransforming avian tumor viruses.

Authors: P H Duesberg; P K Vogt
Journal: Proc Natl Acad Sci U S A Date: 1970-12 Impact factor: 11.205

3. Isolation of murine sarcoma virus-transformed mouse cells which are negative for leukemia virus from agar suspension cultures.

Authors: R H Bassin; N Tuttle; P J Fischinger
Journal: Int J Cancer Date: 1970-07-15 Impact factor: 7.396

4. Rous sarcoma virus: a function required for the maintenance of the transformed state.

Authors: G S Martin
Journal: Nature Date: 1970-09-05 Impact factor: 49.962

5. Temperature sensitive mutants of an avian sarcoma virus.

Authors: K Toyoshima; P K Vogt
Journal: Virology Date: 1969-12 Impact factor: 3.616

6. A virus-induced rhabdomyosarcoma of mice.

Authors: J B Moloney
Journal: Natl Cancer Inst Monogr Date: 1966-09

7. The protovirus hypothesis: speculations on the significance of RNA-directed DNA synthesis for normal development and for carcinogenesis.

Authors: H M Temin
Journal: J Natl Cancer Inst Date: 1971-02 Impact factor: 13.506

8. Rescue of the defective genome of Moloney sarcoma virus from a noninfectious hamster tumor and the production of pseudotype sarcoma viruses with various murine leukemia viruses.

Authors: R J Huebner; J W Hartley; W P Rowe; W T Lane; W I Capps
Journal: Proc Natl Acad Sci U S A Date: 1966-10 Impact factor: 11.205

9. Oncogenes of RNA tumor viruses as determinants of cancer.

Authors: R J Huebner; G J Todaro
Journal: Proc Natl Acad Sci U S A Date: 1969-11 Impact factor: 11.205

10. Forms of deoxyribonucleic acid produced by virions of the ribonucleic acid tumor viruses.

Authors: K F Manly; D F Smoler; E Bromfeld; D Baltimore
Journal: J Virol Date: 1971-01 Impact factor: 5.103

99 in total

1. Characterization of mouse cellular deoxyribonucleic acid homologous to Abelson murine leukemia virus-specific sequences.

Authors: B Dale; B Ozanne
Journal: Mol Cell Biol Date: 1981-08 Impact factor: 4.272

2. An aspect of the origin and evolution of viruses.

Authors: V I Agol
Journal: Orig Life Date: 1976-04

3. Transfer of duck cell DNA sequences to the nucleus of 3T3 cells by Rous sarcoma virus.

Authors: W G Baxt; J L Meinkoth
Journal: Proc Natl Acad Sci U S A Date: 1978-09 Impact factor: 11.205

Review 4. MicroRNA-Based Therapeutic Strategies for Targeting Mutant and Wild Type RAS in Cancer.

Authors: Sriganesh B Sharma; John Michael Ruppert
Journal: Drug Dev Res Date: 2015-08-18 Impact factor: 4.360

5. Host induced alteration of avian sarcoma virus B-77 genome.

Authors: M Shoyab; P D Markham; M A Baluda
Journal: Proc Natl Acad Sci U S A Date: 1975-03 Impact factor: 11.205

6. Deletion mapping of moloney type C virus: polypeptide and nucleic acid expression in different transforming virus isolates.

Authors: W P Parks; R S Howk; A Anisowicz; E M Scolnick
Journal: J Virol Date: 1976-05 Impact factor: 5.103