| Literature DB >> 4126769 |
V A Bokisch, J W Chiao, D Bernstein, R M Krause.
Abstract
The relationship between 7S anti-IgG and antibodies to streptococcal cell wall peptidoglycan was examined for four streptococcal Group C antisera. Homogeneous 7S anti-IgG components in these sera were isolated by means of an IgG immunoadsorbent column. For two of the four antisera, the anti-peptidoglycan activity of the 7S anti-IgG had specificity for the pentapeptide, L-Ala-D-Glu-gamma-L-Lys-D-Ala-D-Ala, the antigenic determinant of peptidoglycan, as well as for the Fc of IgG. Detailed studies on the 7S anti-IgG from one of the antisera revealed that the pentapeptide inhibited the coprecipitation reaction of 7S anti-IgG R3387 with antigen-antibody complexes and the precipitin reaction between 7S anti-IgG R3387 and its anti-idiotype serum.Entities:
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Year: 1973 PMID： 4126769 PMCID： PMC2139434 DOI： 10.1084/jem.138.5.1184
Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307