| Literature DB >> 4125846 |
T Hayashida, P Licht, C S Nicoll.
Abstract
Growth hormone and prolactin were electrophoretically isolated from amphibian pituitaries and then were tested in a radioimmunoassay with labeled rat growth hormone and antiserum to the same hormone. This isolation and purification of the hormones increased the steepness of the slopes of competitive inhibition in this system when compared to those of crude extracts. Both hormones from most species tested showed high immunochemical cross-reactivity, indicating that amphibian growth hormone and prolactin are structurally related to rat growth hormone.Entities:
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Year: 1973 PMID: 4125846 DOI: 10.1126/science.182.4108.169
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728