Literature DB >> 412492

alpha1-Antitrypsin polymorphism in Malaysian Macaca irus.

F Kueppers, J Ganesan.   

Abstract

alpha1-Antitrypsin types were determined in 200 individual specimens of Malaysian Macaca irus. We found the pattern B in 76 samples, BC in 116, and C in 8. Assuming that these patterns are determined by codominant alleles at one locus, this distribution constitutes a significant (P less than 0.001) deviation from Hardy-Weinberg equilibrium, because of an excess of BC and low prevalence of C. We found no clear evidence for the presence of alpha1-antitrypsin deficiency comparable to the situation in man.

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Year:  1977        PMID: 412492     DOI: 10.1007/bf00483978

Source DB:  PubMed          Journal:  Biochem Genet        ISSN: 0006-2928            Impact factor:   1.890


  8 in total

1.  ANTIGEN-ANTIBODY CROSSED ELECTROPHORESIS.

Authors:  C B LAURELL
Journal:  Anal Biochem       Date:  1965-02       Impact factor: 3.365

2.  p-Nitrophenyl-p'-guanidinobenzoate HCl: a new active site titrant for trypsin.

Authors:  T Chase; E Shaw
Journal:  Biochem Biophys Res Commun       Date:  1967-11-30       Impact factor: 3.575

3.  The electrophoretic α1-globulin pattern of serum in α1-antitrypsin deficiency. 1963.

Authors:  Carl-Bertil Laurell; Sten Eriksson
Journal:  COPD       Date:  2013-03       Impact factor: 2.409

Review 4.  The Pi system-inherited variants of serum alpha 1-antitrypsin.

Authors:  M K Fagerhol; C B Laurell
Journal:  Prog Med Genet       Date:  1970

5.  Antigenic similarity of human alpha-1-antitrypsin to a corresponding protein in the serum of non-human primates.

Authors:  F Kueppers
Journal:  Experientia       Date:  1968-12-15

Review 6.  Alpha1-antitrypsin and its deficiency.

Authors:  F Kueppers; L F Black
Journal:  Am Rev Respir Dis       Date:  1974-08

7.  A new deficient variant of alpha1-antitrypsin (MDUARTE). Inability to detect the heterozygous state by antitrypsin phenotyping.

Authors:  J Lieberman; L Gaidulis; S D Klotz
Journal:  Am Rev Respir Dis       Date:  1976-01

8.  A case of inherited deficiency of serum alpha-antitrypsin associated with pulmonary emphysema.

Authors:  W A Briscoe; F Kueppers; A L Davis; A G Bearn
Journal:  Am Rev Respir Dis       Date:  1966-10
  8 in total

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