Literature DB >> 412248

Effect of gold on progression of erosions in rheumatoid arthritis. Better results with early treatment.

R Luukkainen, A Kajander, H Isomäki.   

Abstract

The advance of radiological destruction in 57 patients with definite rheumatoid arthritis was observed for 5-6 years. In all patients gold treatment was started 2-36 months after the onset of the disease. In 18 patients gold was discontinued because of side-effects of other reasons before reaching the total dosage of 500 mg, while the remaining 39 patients received a mean dose of 2030 mg of natriumaurothiomalate. The advance of the radiological destruction was statistically significantly less marked in patients treated with the full gold therapy. The earlier the treatment was initiated, the better was the result.

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Year:  1977        PMID: 412248     DOI: 10.3109/03009747709095448

Source DB:  PubMed          Journal:  Scand J Rheumatol        ISSN: 0300-9742            Impact factor:   3.641


  20 in total

Review 1.  Rheumatology: 5. Diagnosis and management of inflammatory polyarthritis.

Authors:  A Klinkhoff
Journal:  CMAJ       Date:  2000-06-27       Impact factor: 8.262

2.  Prospective six year follow up of patients withdrawn from a randomised study comparing parenteral gold salt and methotrexate.

Authors:  O Sander; G Herborn; E Bock; R Rau
Journal:  Ann Rheum Dis       Date:  1999-05       Impact factor: 19.103

Review 3.  Combination chemotherapy in rheumatoid arthritis.

Authors:  P M Brooks; A C Schwarzer
Journal:  Ann Rheum Dis       Date:  1991-07       Impact factor: 19.103

4.  A simple algorithm to predict the development of radiological erosions in patients with early rheumatoid arthritis: prospective cohort study.

Authors:  P Brennan; B Harrison; E Barrett; K Chakravarty; D Scott; A Silman; D Symmons
Journal:  BMJ       Date:  1996-08-24

5.  Methotrexate therapy in rheumatoid arthritis. Current status.

Authors:  W S Wilke; A H Mackenzie
Journal:  Drugs       Date:  1986-08       Impact factor: 9.546

6.  Radiological evaluation of erosions: a quantitative method for assessing long-term remittive therapy in rheumatoid arthritis.

Authors:  W M O'Brien
Journal:  Br J Clin Pharmacol       Date:  1986       Impact factor: 4.335

Review 7.  Joint damage in rheumatoid arthritis: radiological assessments and the effects of anti-rheumatic drugs.

Authors:  D L Scott; P A Bacon
Journal:  Rheumatol Int       Date:  1985       Impact factor: 2.631

8.  Sustained maintenance of exercise induced muscle strength gains and normal bone mineral density in patients with early rheumatoid arthritis: a 5 year follow up.

Authors:  A Häkkinen; T Sokka; H Kautiainen; A Kotaniemi; P Hannonen
Journal:  Ann Rheum Dis       Date:  2004-08       Impact factor: 19.103

9.  Only high disease activity and positive rheumatoid factor indicate poor prognosis in patients with early rheumatoid arthritis treated with "sawtooth" strategy.

Authors:  T Möttönen; L Paimela; M Leirisalo-Repo; H Kautiainen; J Ilonen; P Hannonen
Journal:  Ann Rheum Dis       Date:  1998-09       Impact factor: 19.103

Review 10.  Treatment of rheumatoid arthritis: a global perspective on the use of antirheumatic drugs.

Authors:  Tuulikki Sokka; Minja Envalds; Theodore Pincus
Journal:  Mod Rheumatol       Date:  2008-04-25       Impact factor: 3.023

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