Literature DB >> 4121027

DNA polymerase activities of human milk.

B I Gerwin, P S Ebert, H C Chopra, S G Smith, J P Kvedar, S Albert, M J Brennan.   

Abstract

DNA polymerases have been partially purified from human milk. A DNA polymerase detected by phosphocellulose chromatography is similar to the enzymes of RNA tumor viruses in that a hybrid of polyriboadenylate and oligodeoxythymidylate is a better template than is DNA. However, this polymerase differed from that of the RNA tumor viruses in its chromatographic behavior. Three different methods of detecting "reverse transcriptase" activity failed to correlate with the donor's family history of cancer.

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Year:  1973        PMID: 4121027     DOI: 10.1126/science.180.4082.198

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Further evidence for oncornaviruses in human milk: the production of cores.

Authors:  S P Feldman; J Schlom; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1973-07       Impact factor: 11.205

Review 2.  Integration of maternal genome into the neonate genome through breast milk mRNA transcripts and reverse transcriptase.

Authors:  M Kemal Irmak; Yesim Oztas; Emin Oztas
Journal:  Theor Biol Med Model       Date:  2012-06-07       Impact factor: 2.432

Review 3.  Human RNA "rumor" viruses: the search for novel human retroviruses in chronic disease.

Authors:  Cécile Voisset; Robin A Weiss; David J Griffiths
Journal:  Microbiol Mol Biol Rev       Date:  2008-03       Impact factor: 13.044

  3 in total

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