Literature DB >> 4117345

Isolation of temperature-sensitive mutants of murine sarcoma virus.

E M Scolnick, J R Stephenson, S A Aaronson.   

Abstract

Three separate murine sarcoma virus nonproducer cell lines have been isolated which are temperature sensitive for the maintenance of transformation. In each case, a viral rather than a cellular genetic mutation is the reason for the temperature-sensitive effect. Superinfection of one of the mutants with murine leukemia virus overcomes the temperature-sensitive change in the transformed state.

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Year:  1972        PMID: 4117345      PMCID: PMC356516     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  22 in total

1.  Genetic stability of the sarcoma viruses in murine and avian sarcoma virus-transformed nonproducer cells.

Authors:  J R Stephenson; E M Scolnick; S A Aaronson
Journal:  Int J Cancer       Date:  1972-05-15       Impact factor: 7.396

2.  Conditional lethal mutants of avian sarcoma viruses. II. Analysis of the temperature-sensitive lesion in ts 75.

Authors:  E Katz; P K Vogt
Journal:  Virology       Date:  1971-12       Impact factor: 3.616

3.  Characteristics of a conditional mutant of Rous sarcoma virus defective in ability to transform cells at high temperature.

Authors:  J M Biquard; P Vigier
Journal:  Virology       Date:  1972-02       Impact factor: 3.616

4.  Isolation of temperature-sensitive mutants of murine leukemia virus.

Authors:  J R Stephenson; R K Reynolds; S A Aaronson
Journal:  Virology       Date:  1972-06       Impact factor: 3.616

5.  Conditional lethal mutants of avian sarcoma viruses. I. Physiology of ts 75 and ts 149.

Authors:  R R Friis; K Toyoshima; P K Vogt
Journal:  Virology       Date:  1971-02       Impact factor: 3.616

6.  Temperature sensitive mutants of an avian sarcoma virus.

Authors:  K Toyoshima; P K Vogt
Journal:  Virology       Date:  1969-12       Impact factor: 3.616

7.  A virus-induced rhabdomyosarcoma of mice.

Authors:  J B Moloney
Journal:  Natl Cancer Inst Monogr       Date:  1966-09

8.  A nuclease specific for heat-denatured DNA in isolated from a product of Aspergillus oryzae.

Authors:  T Ando
Journal:  Biochim Biophys Acta       Date:  1966-01-18

9.  Production of altered cell foci in tissue culture by defective Moloney sarcoma virus particles.

Authors:  J W Hartley; W P Rowe
Journal:  Proc Natl Acad Sci U S A       Date:  1966-04       Impact factor: 11.205

10.  Mutation causing temperature-sensitive expression of cell transformation by a tumor virus (SV40-3T3 mouse cells-growth control).

Authors:  H C Renger; C Basilico
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

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  17 in total

1.  Temperature-sensitive mutants of chemically transformed epithelial cells.

Authors:  N Yamaguchi; I B Weinstein
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

2.  Use of epithelial cell cultures for studies on the mechanism of transformation by chemical carcinogens.

Authors:  I B Weinstein; N Yamaguchi; R Gebert; M E Kaighn
Journal:  In Vitro       Date:  1975 May-Jun

3.  Development and analysis of a transformation-defective mutant of Harvey murine sarcoma tk virus and its gene product.

Authors:  M O Weeks; G L Hager; R Lowe; E M Scolnick
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

4.  Identification of Rauscher murine leukemia virus-specific mRNAs for the synthesis of gag- and env-gene products.

Authors:  D V Zaane; A L Gielkens; W G Hesselink; H P Bloemers
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

5.  Selection of revertants of Kirsten sarcoma virus transformed nonproducer BALB-3T3 cells.

Authors:  B Ozanne; A Vogel
Journal:  J Virol       Date:  1974-08       Impact factor: 5.103

6.  Demonstration of a cell-surface antigen associated with murine sarcoma virus by immunoelectron microscopy.

Authors:  T Aoki; J R Stephenson; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

7.  Decrease in epidermal growth factor receptor levels and production of material enhancing epidermal growth factor binding accompany the temperature-dependent changes from normal to transformed phenotype.

Authors:  P Guinivan; R L Ladda
Journal:  Proc Natl Acad Sci U S A       Date:  1979-07       Impact factor: 11.205

8.  Transforming growth factor(s) production enables cells to grow in the absence of serum: an autocrine system.

Authors:  P L Kaplan; M Anderson; B Ozanne
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

9.  Toward a model for the molecular genetics of carcinogenesis in rats.

Authors:  P C Kimball; M C Simon; N K Mishra
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

10.  Expression of the major internal viral polypeptide in cells transformed by wild-type and temperature-sensitive murine sarcoma virus.

Authors:  G Spira; G R Dreesman; M Benyesh-Melnick; S Kit; K D Somers
Journal:  J Virol       Date:  1974-11       Impact factor: 5.103

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