Literature DB >> 4116712

Cytotoxic antibody in normal human serums reactive with tumor cells from acute lymphocytic leukemia.

W B Bias, G W Santos, P J Burke, G M Mullins, R L Humphrey.   

Abstract

Serums showing complement-dependent cytotoxic reactions to acute lymphocytic leukemia cells were detected in three normal unimmunized subjects. These serums were reactive with tumor cells from 514 (514 tested) acute lymphocytic leukemia patients, and three (12 tested) patients with acute myelocytic leukemia; they did not react with tumor cells from patients with acute monocytic leukemia (two tested), with chronic lymphocytic leukemia (two tested) or with leukolymphosarcoma (two tested); nor did they react with normal lymphocytes from 52 different donors. These reactive serums appear to recognize antigens primarily associated with acute lymphocytic leukemia.

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Year:  1972        PMID： 4116712     DOI： 10.1126/science.178.4058.304

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Immunological studies in acute leukemia.

Authors:  G W Santos; P N Anderson; D L Klein; W B Bias; B Z Schacter; G M Mullins; P J Burke
Journal:  Trans Am Clin Climatol Assoc       Date:  1977

2.  Cat leukemia and the cluster controversy.

Authors:  J E Parker
Journal:  Can Med Assoc J       Date:  1978-03-04       Impact factor: 8.262

3.  Tumour immunity and immunotherapy.

Authors:  G M Mullins
Journal:  Ir J Med Sci       Date:  1978-09       Impact factor: 1.568

4.  Antisera against leukaemia-associated antigens on human lymphocytes.

Authors:  C C Hsu; G E Marti; K K Mittal
Journal:  Clin Exp Immunol       Date:  1977-03       Impact factor: 4.330

5.  Antigen heterogeneity of human B and T lymphocytes.

Authors:  E M Rabellino; H M Grey; S LaForge; B Pirofsky; N Kashiwagi; A Malley
Journal:  J Clin Invest       Date:  1976-02       Impact factor: 14.808

6.  Expression of blood group-like antigens on the T lymphocytes of acute leukaemia patients in remission.

Authors:  S Pullen; P Hersey
Journal:  Clin Exp Immunol       Date:  1980-02       Impact factor: 4.330

7.  Specificity of heteroantisera to human acute leukemia-associated antigens.

Authors:  M A Baker; K Ramachandar; R N Taub
Journal:  J Clin Invest       Date:  1974-12       Impact factor: 14.808

8.  Human B-lymphocyte antigens expressed by lymphocytic and myelocytic leukemia cells. I. Detection by rabbit antisera.

Authors:  R Billing; B Rafizadeh; I Drew; G Hartman; R Gale; P Terasaki
Journal:  J Exp Med       Date:  1976-07-01       Impact factor: 14.307

9.  Surface antigens in acute myeloblastic leukaemia: a study using heterologous antisera.

Authors:  L Tupchong; I C MacLennan
Journal:  Br J Cancer       Date:  1978-10       Impact factor: 7.640

10.  Radioimmunoassay of tumour specific transplantation antigen of a chemically induced rat sarcoma: circulating soluble tumour antigen in tumour bearers.

Authors:  D M Thomson; V Sellens; S Eccles; P Alexander
Journal:  Br J Cancer       Date:  1973-11       Impact factor: 7.640
  10 in total

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