| Literature DB >> 4114974 |
R G Wyllie, G S Hill, G Murray, P W Ramsden, R H Heptinstall.
Abstract
Reserpine is able to exert a pronounced inhibitory effect on the development of papillary necrosis following the administration of bromoethylamine hydrobromide to the rat. This inhibitory effect has been observed using light microscopy, histochemistry, indigo carmine excretion and urine output. These observations suggest that vasoconstriction may play a significant role in the pathogenesis of papillary necrosis, but the evidence for this is incomplete.Entities:
Mesh:
Substances:
Year: 1972 PMID: 4114974 PMCID: PMC2032678
Source DB: PubMed Journal: Am J Pathol ISSN: 0002-9440 Impact factor: 4.307