Literature DB >> 411490

Purified human liver acid beta-D-galactosidases possessing activity towards G(M1)-ganglioside and lactosylceramide.

A L Miller, R G Frost, J S O'Brien.   

Abstract

Our studies with purified human liver acid beta-D-galactosidases (EC 3.2.1.23) indicate that 4-methylumbelliferyl beta-D-galactosidase and G(M1)-ganglioside beta-D-galactosidase activities are identical with lactosylceramidase II activity. Evidence for this includes co-purification of all enzyme activities by affinity chromatography to yield a single band on polyacrylamide-gel electrophoresis and coincident elution from Sepharose 6B of all three enzyme activities.

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Year:  1977        PMID： 411490      PMCID： PMC1164944          DOI： 10.1042/bj1650591

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  20 in total

1.  Lactosyl ceramidosis: normal activity for two lactosyl ceramide beta-galactosidases.

Authors:  D A Wenger; M Sattler; C Clark; H Tanaka; K Suzuki; G Dawson
Journal:  Science       Date:  1975-06-27       Impact factor: 47.728

2.  PREPARATIVE ELECTROPHORESIS OF PROTEINS IN ACRYLAMIDE GELS.

Authors:  J V MAIZEL
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Purification of human liver acid beta-D-galactosidases using affinity chromatography.

Authors:  A L Miller; R G Frost; J O'Brien
Journal:  Anal Biochem       Date:  1976-08       Impact factor: 3.365

5.  Stimulation of acid beta-galactosidase activity by chloride ions.

Authors:  M W Ho; J S O'Brien
Journal:  Clin Chim Acta       Date:  1970-11       Impact factor: 3.786

6.  Specificities of the two genetically distinct beta-galactosidases in human sphingolipidoses.

Authors:  H Tanaka; K Suzuki
Journal:  Arch Biochem Biophys       Date:  1976-07       Impact factor: 4.013

7.  Specificity and multiple forms of beta-galactosidase in the rat.

Authors:  A J Furth; D Robinson
Journal:  Biochem J       Date:  1965-10       Impact factor: 3.857

8.  Activity of human hepatic beta-galactosidase toward natural glycosphingolipid substrates.

Authors:  H Tanaka; M Meisler; K Suzuki
Journal:  Biochim Biophys Acta       Date:  1975-09-19

9.  Lactosylceramide beta-galactosidase in human sphingolipidoses. Evidence for two genetically distinct enzymes.

Authors:  H Tanaka; K Suzuki
Journal:  J Biol Chem       Date:  1975-03-25       Impact factor: 5.157

10.  Lactosylceramidase assays for diagnosis of globoid cell leukodystrophy and GM1-gangliosidosis.

Authors:  H Tanaka; K Suzuki
Journal:  Clin Chim Acta       Date:  1977-03-01       Impact factor: 3.786
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  3 in total

Review 1.  Binding interactions of glycoproteins with lectins.

Authors:  J T Dulaney
Journal:  Mol Cell Biochem       Date:  1978-10-13       Impact factor: 3.396

2.  Characterization of purified human liver acid beta-D-galactosidases A2 and A3.

Authors:  R G Frost; E W Holmes; A G Norden; J S O'Brien
Journal:  Biochem J       Date:  1978-10-01       Impact factor: 3.857

3.  Purification and immunological quantification of rat liver lysosomal glycosidases.

Authors:  P C de Groen; G D LeSage; P S Tietz; N F LaRusso
Journal:  Biochem J       Date:  1989-11-15       Impact factor: 3.857
  3 in total

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