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Literature DB >> 4111169

Metastases and the normalization of tumour blood vessels by ICRF 159: a new type of drug action.

Abstract

Profound modification of the structure and arrangement of the blood vessels has been shown in tumours after treatment with ICRF 159. X-ray angiography, carbon black (Pelikan ink) labelling, and intravital staining with lissamine green were used to demonstrate the changes. Alteration of the morphology of the blood vessels at the edge of a tumour may affect the escape of malignant cells and the rate of blood flow (and thus the concentration of anticancer drugs) through the tumour.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1972 PMID： 4111169 PMCID： PMC1787556 DOI： 10.1136/bmj.1.5800.597

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

9 in total

1. Changes of oxygen tension in tumours induced by vasoconstrictor and vasodilator drugs.

Authors: D B CATER; C M GRIGSON; D A WATKINSON
Journal: Acta radiol Date: 1962-12 Impact factor: 1.990

2. THE DEMONSTRATION OF BRONCHOSPASM IN ANAPHYLAXIS BY RADIOGRAPHY.

Authors: W E PARISH; A R AKESTER; D M GREGG
Journal: Int Arch Allergy Appl Immunol Date: 1964

3. Angiography of malignant tumors in mice.

Authors: A R MARGULIS; E CARLSSON; W H McALISTER
Journal: Acta radiol Date: 1961-09 Impact factor: 1.990

4. Effect of endotoxin from Serratia marcescens on the permeability of vessels in hepatomas and carrageenin granulomas of rats.

Authors: N T Oswald; D B Cater
Journal: Br J Exp Pathol Date: 1969-02

5. Control of malignant metastases by ICRF l59.

Authors: K Hellmann; K Burrage
Journal: Nature Date: 1969-10-18 Impact factor: 49.962

6. Drug-induced inhibition of tumour cell dissemination.

Authors: K Burrage; K Hellmann; A J Salsbury
Journal: Br J Pharmacol Date: 1970-05 Impact factor: 8.739

7. Inhibition of metastatic spread by I.C.R.F. 159: selective deletion of a malignant characteristic.

Authors: A J Salsbury; K Burrage; K Hellmann
Journal: Br Med J Date: 1970-11-07

8. Inflammatory changes in tumour vessels after systemic 5-hydroxytryptamine, bradykinin, kallikrein, or lysolecithin.

Authors: D B Cater; C R Taylor
Journal: Br J Cancer Date: 1966-09 Impact factor: 7.640

9. Studies on inflammation. II. The site of action of histamine and serotonin along the vascular tree: a topographic study.

Authors: G MAJNO; G E PALADE; G I SCHOEFL
Journal: J Biophys Biochem Cytol Date: 1961-12

9 in total

39 in total

Review 1. Improving delivery and efficacy of nanomedicines in solid tumors: role of tumor priming.

Authors: Jie Wang; Ze Lu; Yue Gao; M Guillaume Wientjes; Jessie L-S Au
Journal: Nanomedicine (Lond) Date: 2011-11 Impact factor: 5.307

2. Improved intratumoral oxygenation through vascular normalization increases glioma sensitivity to ionizing radiation.

Authors: Mackenzie C McGee; J Blair Hamner; Regan F Williams; Shannon F Rosati; Thomas L Sims; Catherine Y Ng; M Waleed Gaber; Christopher Calabrese; Jianrong Wu; Amit C Nathwani; Christopher Duntsch; Thomas E Merchant; Andrew M Davidoff
Journal: Int J Radiat Oncol Biol Phys Date: 2010-04 Impact factor: 7.038

Review 3. Tumour angiogenesis.

Authors: F Arnold
Journal: Ann R Coll Surg Engl Date: 1985-09 Impact factor: 1.891

4. Combined razoxane and radiotherapy for melanoma brain metastases. a retrospective analysis.

Authors: Walter Rhomberg; Helmut Eiter; Franz Boehler; Christoph Saely; Robert Strohal
Journal: J Neurooncol Date: 2005-09 Impact factor: 4.130

Review 5. Lysosomes in cancer cells.

Authors: A C Allison
Journal: J Clin Pathol Suppl (R Coll Pathol) Date: 1974

6. Combined treatment of the Walker tumour with radiotherapy and ICRF 159.

Authors: K Norpoth; A Schaphaus; H Ziegler; U Witting
Journal: Z Krebsforsch Klin Onkol Cancer Res Clin Oncol Date: 1974

Review 7. [Angiosarcoma of the right atrium: local control via low radiation doses and razoxane. A case report].

Authors: W Rhomberg; M Grass
Journal: Strahlenther Onkol Date: 1999-03 Impact factor: 3.621

8. Antitumor activity of MST-16, a novel derivative of bis(2,6-dioxopiperazine), in murine tumor models.

Authors: T Narita; S Yaguchi; T Komatsu; M Takase; A Hoshino; M Inaba; S Tsukagoshi
Journal: Cancer Chemother Pharmacol Date: 1990 Impact factor: 3.333

9. An evaluation of the effectiveness and safety of razoxane when used as an adjunct to surgery in colo-rectal cancer. Report of a controlled randomised study of 603 patients.

Authors: R D Kingston; J W Fielding; M K Palmer
Journal: Int J Colorectal Dis Date: 1993-07 Impact factor: 2.571

10. Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane.

Authors: S L Maloney; D C Sullivan; S Suchting; J M J Herbert; E M Rabai; Z Nagy; J Barker; S Sundar; R Bicknell
Journal: Br J Cancer Date: 2009-09-15 Impact factor: 7.640