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Literature DB >> 4110790

Lysosomal enzyme cytochemistry in acute leukaemia.

J R Mann, J S Simpson, R M Munkley, J Stuart.

Abstract

A cytochemical study of the lysosomal enzyme beta-glucuronidase in 60 cases of acute leukaemia has shown a qualitative difference in the cytoplasmic distribution of the enzyme between blast cells of the lymphoid and myeloid cell series. This difference provides a useful additional method for cytochemical classification of cell type and is superior in this respect to the other lysosomal enzymes studied (aryl sulphatase and acid phosphatase). The beta-glucuronidase reaction is recommended in those cases of acute leukaemia in which the periodic acid-Schiff reaction is negative or equivocal.

Entities: Chemical Disease Gene

Mesh：

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Year: 1971 PMID： 4110790 PMCID： PMC477194 DOI： 10.1136/jcp.24.9.831

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

12 in total

1. CYTOCHEMICAL DEMONSTRATION OF ACID PHOSPHATASE IN HEMATOPOIETIC CELLS IN HEALTH AND IN VARIOUS HEMATOLOGICAL DISORDERS USING AZO DYE TECHNIQUES.

Authors: L S KAPLOW; M S BURSTONE
Journal: J Histochem Cytochem Date: 1964-11 Impact factor: 2.479

10. THE CYTOLOGIC DEMONSTRATION OF BETA-GLUCURONIDASE EMPLOYING NAPHTHOL AS-BI GLUCURONIDE AND HEXAZONIUM PARAROSANILIN; A PRELIMINARY REPORT.

Authors: M HAYASHI; Y NAKAJIMA; W H FISHMAN
Journal: J Histochem Cytochem Date: 1964-04 Impact factor: 2.479

3 in total

Lysosomal enzyme cytochemistry in acute leukaemia.

1. CYTOCHEMICAL DEMONSTRATION OF ACID PHOSPHATASE IN HEMATOPOIETIC CELLS IN HEALTH AND IN VARIOUS HEMATOLOGICAL DISORDERS USING AZO DYE TECHNIQUES.

2. A histochemical method for sulfatase activity in hemic cells and organ imprints.

3. ACID PHOSPHATASE ACTIVITY IN NORMAL HUMAN BLOOD AND BONE MARROW CELLS AS DEMONSTRATED BY THE AZO DYE METHOD.

4. NUCLEAR ARYLSULFATASE ACTIVITY IN PRIMITIVE HEMIC CELLS.

5. Acid phosphatase activity in human blood cells.

6. Cytochemical demonstration of beta-glucuronidase activity in blood and bone marrow cells.

7. An evaluation of aryl sulphatase activity in leukaemic cells.

8. Histochemical demonstration of leucocyte acid phosphatase in health and in disease.

9. An evaluation of nuclear aryl sulphatase activity as an aid to the cytological diagnosis of acute leukaemia.

10. THE CYTOLOGIC DEMONSTRATION OF BETA-GLUCURONIDASE EMPLOYING NAPHTHOL AS-BI GLUCURONIDE AND HEXAZONIUM PARAROSANILIN; A PRELIMINARY REPORT.

Review 1. Enzyme cytochemistry of blood and marrow cells.

Review 2. Cytochemistry of lymphoid cells: a review of findings in the normal and leukaemic state.

3. Differential diagnostic value of acid phosphatase and beta-glucuronidase in acute leukaemia.