| Literature DB >> 410562 |
J C Chermann, J Gruest, L Montagnier, F Wendling, P Tambourin, M Perrin, F Pochon, C Ducrocq, C Rivalle, E Bisagni.
Abstract
Among newly synthesized compounds derived from the dipyrido [4,3-b] [3,4-f] indole nucleus, two have proved to be particularly active in vitro and in vivo. Their cytotoxic effects on cultured cells have been determined. At non toxic doses, they displayed a pronounced inhibitory effect on experimental L1210 Leukemia. These compounds have a strong affinity for DNA molecules.Entities:
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Year: 1977 PMID： 410562
Source DB: PubMed Journal: C R Acad Hebd Seances Acad Sci D