Literature DB >> 409721

Retention of amylase in the secretory granules of parotid gland after extensive release of Ca++ by ionophore A-23187.

Y Flashner, M Schramm.   

Abstract

The effect of the ionophore A-23187 was tested on isolated secretory granules of rat parotid gland. The ionophore caused extensive release of calcium from the granules without effecting release of amylase or other secretory proteins. It is therefore concluded that the role of calcium in the granules is probably not that of a stabilizing agent.

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Year:  1977        PMID： 409721      PMCID： PMC2110102          DOI： 10.1083/jcb.74.3.789

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  14 in total

1.  DISTRIBUTION OF METALS AND CATECHOLAMINES IN BOVINE ADRENAL MEDULLA SUB-CELLULAR FRACTIONS.

Authors:  J L BOROWITZ; K FUWA; N WEINER
Journal:  Nature       Date:  1965-01-02       Impact factor: 49.962

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  The role of calcium in fly salivary gland secretion analyzed with the ionophore A-23187.

Authors:  W T Prince; H Rasmussen; M J Berridge
Journal:  Biochim Biophys Acta       Date:  1973-11-02

4.  Calcium and the exportable protein in rat parotid gland. Parallel subcellular distribution and concomitant secretion.

Authors:  D Wallach; M Schramm
Journal:  Eur J Biochem       Date:  1971-08-16

5.  Energy production in rat parotid gland. Relation tonzyme secretion and effects of caium.

Authors:  H Feinstein; M Schramm
Journal:  Eur J Biochem       Date:  1970-03-01

6.  A23187: a divalent cation ionophore.

Authors:  P W Reed; H A Lardy
Journal:  J Biol Chem       Date:  1972-11-10       Impact factor: 5.157

7.  ATP-dependent calcium uptake by microsomal preparations from rat parotid and submaxillary glands.

Authors:  Z Selinger; E Naim; M Lasser
Journal:  Biochim Biophys Acta       Date:  1970-04-21

8.  Calcium ionophores and movement of calcium ions following the physiological stimulus to a secretory process.

Authors:  J C Foreman; J L Mongar; B D Gomperts
Journal:  Nature       Date:  1973-10-05       Impact factor: 49.962

9.  A calcium ionophore simulating the action of epinephrine on the alpha-adrenergic receptor.

Authors:  Z Selinger; S Eimerl; M Schramm
Journal:  Proc Natl Acad Sci U S A       Date:  1974-01       Impact factor: 11.205

10.  Calcium and pancreatic secretion. I. Subcellular distribution of calcium and magnesium in the exocrine pancreas of the guinea pig.

Authors:  F Clemente; J Meldolesi
Journal:  J Cell Biol       Date:  1975-04       Impact factor: 10.539
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  1 in total

Review 1.  Parotid secretory granules: crossroads of secretory pathways and protein storage.

Authors:  S-U Gorr; S G Venkatesh; D S Darling
Journal:  J Dent Res       Date:  2005-06       Impact factor: 6.116
  1 in total

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