Literature DB >> 4093851

Antitumor activity of aqueous extracts of marine animals.

T Sasaki, N A Uchida, H Uchida, N Takasuka, H Kamiya, Y Endo, M Tanaka, T Hayashi, Y Shimizu.   

Abstract

Aqueous extracts (macromolecule fractions in particular) of 25 species of well-known marine animals were tested for their antitumor activity against transplanted sarcoma 180 solid form in ICR mice. All of the macromolecule fractions from the extracts of animals in the shellfish category except that of Mytilus edulis inhibited the growth of sarcoma 180. The use of aqueous extracts from Strongylocentrotus nudus, Halocynthia hilgendorfi f. ritteri, Styela plicata, Ecteinascidia turbinata, and Megabalanus rosa also revealed relatively high inhibition ratios of over 60%.

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Year:  1985        PMID： 4093851     DOI： 10.1248/bpb1978.8.969

Source DB:  PubMed          Journal:  J Pharmacobiodyn        ISSN： 0386-846X


  2 in total

1.  A new cytotoxic fatty acid (5Z,9Z)-22-methyl-5,9-tetracosadienoic acid and the sterols from the far eastern sponge Geodinella robusta.

Authors:  Tatyana N Makarieva; Elena A Santalova; Irina A Gorshkova; Andrei S Dmitrenok; Alla G Guzii; Vladimir I Gorbach; Vassilii I Svetashev; Valentin A Stonik
Journal:  Lipids       Date:  2002-01       Impact factor: 1.880

2.  Oncostatic and immunomodulatory effects of a glycoprotein fraction from water extract of abalone, Haliotis discus hannai.

Authors:  H Uchida; T Sasaki; N A Uchida; N Takasuka; Y Endo; H Kamiya
Journal:  Cancer Immunol Immunother       Date:  1987       Impact factor: 6.968
  2 in total

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