Literature DB >> 4093335

Synthesis and antibacterial activity of some derivatives of the antibiotic thermorubin.

B Cavalleri, M Turconi, R Pallanza.   

Abstract

A series of derivatives has been prepared from the antibiotic thermorubin, some of which show a substantial modification of the original structure. The antibacterial activities are reported.

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Year:  1985        PMID： 4093335     DOI： 10.7164/antibiotics.38.1752

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  2 in total

Review 1.  Ribosome-targeting antibiotics and mechanisms of bacterial resistance.

Authors:  Daniel N Wilson
Journal:  Nat Rev Microbiol       Date:  2014-01       Impact factor: 60.633

2.  The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge B2a of the ribosome.

Authors:  David Bulkley; Francis Johnson; Thomas A Steitz
Journal:  J Mol Biol       Date:  2012-01-02       Impact factor: 5.469
  2 in total

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