Vegetating iodides after an intravenous pyelogram.

A 68-year-old woman treated by hemodialysis for chronic renal failure received 30.4 g iodine for an intravenous pyelogram. Three days later, she was covered by aseptic pustules which quickly evolved into vegetating masses on the face. Skin pathology showed dermo-epidermal necrosis with dermal polymorphonuclear infiltrates, sometimes pycnotic, and necrotizing vasculitis. Serum iodine was far above normal values. Hemodialysis and local care resulted in good healing within 1.5 month. Four similar cases occurring in patients with renal failure are mentioned in literature.