Blood pressure in patients with primary hyperparathyroidism before and after parathyroidectomy.

Studies were performed in 86 patients with proven primary hyperparathyroidism pre-operatively and 6-7 months after parathyroidectomy. The 29% incidence of hypertension between patients with primary hyperparathyroidism is higher as compared with the incidence of hypertension in the general population. Systolic and diastolic blood pressures were significantly higher in patients with primary hyperparathyroidism before operation than after parathyroidectomy (p less than 0.001). In patients hypertensive before operation both the systolic and diastolic blood pressure significantly fell after parathyroidectomy (p less than 0.001). The blood pressure was found to have normalized in 13 of the 25 patients with hypertension. Renal damage and changes in renin levels are not the mechanisms in the production of hypertension in hyperparathyroid patients.