Literature DB >> 4091794

Isolation and amino acid sequence of a short-chain neurotoxin from an Australian elapid snake, Pseudechis australis.

C Takasaki, N Tamiya.   

Abstract

A short-chain neurotoxin Pseudechis australis a (toxin Pa a) was isolated from the venom of an Australian elapid snake Pseudechis australis (king brown snake) by sequential chromatography on CM-cellulose, Sephadex G-50 and CM-cellulose columns. Toxin Pa a has an LD50 (intravenous) value of 76 micrograms/kg body wt. in mice and consists of 62 amino acid residues. The amino acid sequence of Pa a shows considerable homology with those of short-chain neurotoxins of elapid snakes, especially of true sea snakes.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 4091794      PMCID： PMC1152888          DOI： 10.1042/bj2320367

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  16 in total

1.  The preparation and enzymatic hydrolysis of reduced and S-carboxymethylated proteins.

Authors:  A M CRESTFIELD; S MOORE; W H STEIN
Journal:  J Biol Chem       Date:  1963-02       Impact factor: 5.157

2.  Amino acid sequences of the two principal neurotoxins of Enhydrina schistosa venom.

Authors:  L Fryklund; D Eaker; E Karlsson
Journal:  Biochemistry       Date:  1972-11-21       Impact factor: 3.162

3.  Snake venom toxins. The amino acid sequences of two toxins from Dendroaspis jamesoni kaimosae (Jameson's mamba) venom.

Authors:  A J Strydom
Journal:  Biochim Biophys Acta       Date:  1973-12-06

4.  A gas-liquid solid phase peptide and protein sequenator.

Authors:  R M Hewick; M W Hunkapiller; L E Hood; W J Dreyer
Journal:  J Biol Chem       Date:  1981-08-10       Impact factor: 5.157

5.  Isolation, properties and amino acid sequences of three neurotoxins from the venom of a sea snake, Aipysurus laevis.

Authors:  N Maeda; N Tamiya
Journal:  Biochem J       Date:  1976-01-01       Impact factor: 3.857

6.  Amino acid sequences of neurotoxins I and III of the elapidae snake Naja mossambica massambica.

Authors:  J Gregoire; H Rochat
Journal:  Eur J Biochem       Date:  1977-10-17

7.  The isolation, properties and amino acid sequence of erabutoxin c, a minor neurotoxic component of the venom of a sea snake Katicauda semifasciata.

Authors:  N Tamiya; H Abe
Journal:  Biochem J       Date:  1972-11       Impact factor: 3.857

8.  A lethal myotoxin isolated from the venom of the Australian king brown snake (Pseudechis australis).

Authors:  T M Leonardi; M E Howden; I Spence
Journal:  Toxicon       Date:  1979       Impact factor: 3.033

9.  Isolation, properties and amino acid sequence of a long-chain neurotoxin, Acanthophis antarcticus b, from the venom of an Australian snake (the common death adder, Acanthophis antarcticus).

Authors:  H S Kim; N Tamiya
Journal:  Biochem J       Date:  1981-03-01       Impact factor: 3.857

10.  Studies on sea-snake venoms. Crystallization of erabutoxins a and b from Laticauda semifasciata venom.

Authors:  N Tamiya; H Arai
Journal:  Biochem J       Date:  1966-06       Impact factor: 3.857
View more
  3 in total

1.  Pseudechetoxin: a peptide blocker of cyclic nucleotide-gated ion channels.

Authors:  R L Brown; T L Haley; K A West; J W Crabb
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-19       Impact factor: 11.205

2.  Isolation, properties and amino acid sequences of a phospholipase A2 and its homologue without activity from the venom of a sea snake, Laticauda colubrina, from the Solomon Islands.

Authors:  C Takasaki; S Kimura; Y Kokubun; N Tamiya
Journal:  Biochem J       Date:  1988-08-01       Impact factor: 3.857

Review 3.  Studies on sea snake venom.

Authors:  Nobuo Tamiya; Tatsuhiko Yagi
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2011       Impact factor: 3.493
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.