Literature DB >> 408923

Swine influenza virus vaccine: potentiation of antibody responses in rhesus monkeys.

E L Stephen, D E Hilmas, J A Mangiafico, H B Levy.   

Abstract

Polyriboinosinic-polyribocytidylic acid stabilized with poly-L-lysine and carboxymethylcellulose [poly(ICLC)] enhances the antibody response in rhesus monkeys immunized with swine influenza virus subunit vaccine. Monkeys given the vaccine-adjuvant combination had earlier and significantly (P less than .05) higher titers by 14 days compared to those that received vaccine alone. The potentiation of the antibody response of young monkeys given a split-virus vaccine in combination with poly(ICLC) suggests that this vaccine-adjuvant combination may similarly provide a potentially useful alternative approach to the immunization of pediatric and young adult age groups against swine influenza.

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Year:  1977        PMID： 408923     DOI： 10.1126/science.408923

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.

Authors:  Barbara J Flynn; Kathrin Kastenmüller; Ulrike Wille-Reece; Georgia D Tomaras; Munir Alam; Ross W Lindsay; Andres M Salazar; Beatriz Perdiguero; Carmen E Gomez; Ralf Wagner; Mariano Esteban; Chae G Park; Christine Trumpfheller; Tibor Keler; Giuseppe Pantaleo; Ralph M Steinman; Robert Seder
Journal:  Proc Natl Acad Sci U S A       Date:  2011-04-05       Impact factor: 11.205

Review 2.  The use of nonhuman primates in research on seasonal, pandemic and avian influenza, 1893-2014.

Authors:  A Sally Davis; Jeffery K Taubenberger; Mike Bray
Journal:  Antiviral Res       Date:  2015-03-05       Impact factor: 5.970

3.  Enhancement of the immunogenicity of phase I antigen of Coxiella burnetii.

Authors:  R F Wachter; G P Briggs; C E Pedersen
Journal:  Infect Immun       Date:  1978-11       Impact factor: 3.441

4.  Adjuvant effects of low doses of a nuclease-resistant derivative of polyinosinic acid . polycytidylic acid on antibody responses of monkeys to inactivated Venezuelan equine encephalomyelitis virus vaccine.

Authors:  D G Harrington; C L Crabbs; D E Hilmas; J R Brown; G A Higbee; F E Cole; H B Levy
Journal:  Infect Immun       Date:  1979-04       Impact factor: 3.441

5.  Variations in the contribution of induced interferon and adjuvanticity to the antiviral effect of different polyinosinic acid . polycytidylic acid formulations in mice infected with encephalomyocarditis virus.

Authors:  N Stebbing; I J Lindley; K M Dawson
Journal:  Infect Immun       Date:  1980-09       Impact factor: 3.441

6.  Comparison of effects of adjuvants on efficacy of virion envelope herpes simplex virus vaccine against labial infection of BALB/c mice.

Authors:  T A Thomson; J Hilfenhaus; H Moser; P S Morahan
Journal:  Infect Immun       Date:  1983-08       Impact factor: 3.441

7.  Protectivity of herpes simplex virus antigens: studies in mice on the adjuvant effect of PICLC and on the dependence of protection on T cell competence.

Authors:  J Hilfenhaus; H Christ; R Köhler; H Moser; H Kirchner; H B Levy
Journal:  Med Microbiol Immunol       Date:  1981       Impact factor: 3.402

8.  Trial Watch: Experimental Toll-like receptor agonists for cancer therapy.

Authors:  Lorenzo Galluzzi; Erika Vacchelli; Alexander Eggermont; Wolf Hervé Fridman; Jerome Galon; Catherine Sautès-Fridman; Eric Tartour; Laurence Zitvogel; Guido Kroemer
Journal:  Oncoimmunology       Date:  2012-08-01       Impact factor: 8.110

9.  Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques.

Authors:  Christiane Stahl-Hennig; Martin Eisenblätter; Edith Jasny; Tamara Rzehak; Klara Tenner-Racz; Christine Trumpfheller; Andres M Salazar; Klaus Uberla; Karen Nieto; Jürgen Kleinschmidt; Reiner Schulte; Lutz Gissmann; Martin Müller; Anna Sacher; Paul Racz; Ralph M Steinman; Mariagrazia Uguccioni; Ralf Ignatius
Journal:  PLoS Pathog       Date:  2009-04-10       Impact factor: 6.823

Review 10.  TLR3 agonists: RGC100, ARNAX, and poly-IC: a comparative review.

Authors:  Asma Komal; Mamoona Noreen; Attalla F El-Kott
Journal:  Immunol Res       Date:  2021-06-19       Impact factor: 2.829
  10 in total

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