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Literature DB >> 408844

Sleep deprivation deficits and their reversal by d- and l-amphetamine.

Abstract

Vigilance performance, waking EEG patterns and mood were studied before and after one night of sleep deprivation in normal males. The effects of d-amphetamine 10 mg, l-amphetamine 10 mg and placebo on these measures were compared. Changes were found in all three measures after one night of sleep-deprivation. d-Amphetamine was more powerful than l-amphetamine in reversing sleep deprivation effects on vigilance and on waking EEG.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1977 PMID： 408844 DOI： 10.1007/bf00426490

Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530

16 in total

1. Electroencephalogram and sleep deprivation.

Authors: J C ARMINGTON; L L MITNICK
Journal: J Appl Physiol Date: 1959-03 Impact factor: 3.531

2. The psychological effects of 205 hours of sleep deprivation.

Authors: R O Pasnau; P Naitoh; S Stier; E J Kollar
Journal: Arch Gen Psychiatry Date: 1968-04

3. Magnesium pemoline: stimulant effects on performance of fatigued subjects.

Authors: S Gelfand; L D Clark; E W Herbert; D M Gelfand; E D Holmes
Journal: Clin Pharmacol Ther Date: 1968 Jan-Feb Impact factor: 6.875

4. A research report on the anti-fatigue effects of magnesium pemoline.

Authors: M H Orzack; C L Taylor; C Kornetsky
Journal: Psychopharmacologia Date: 1968

5. Quantification of sleepiness: a new approach.

Authors: E Hoddes; V Zarcone; H Smythe; R Phillips; W C Dement
Journal: Psychophysiology Date: 1973-07 Impact factor: 4.016

6. Dopamine and norepinephrine uptake by rat brain synaptosomes: relative inhibitory potencies of 1- and d-amphetamine and amantadine.

Authors: J E Thornburg; K E Moore
Journal: Res Commun Chem Pathol Pharmacol Date: 1973-01

Sleep deprivation deficits and their reversal by d- and l-amphetamine.

1. Electroencephalogram and sleep deprivation.

2. The psychological effects of 205 hours of sleep deprivation.

3. Magnesium pemoline: stimulant effects on performance of fatigued subjects.

4. A research report on the anti-fatigue effects of magnesium pemoline.

5. Quantification of sleepiness: a new approach.

6. Dopamine and norepinephrine uptake by rat brain synaptosomes: relative inhibitory potencies of 1- and d-amphetamine and amantadine.

7. The structure of mood: a comparison between sleep deprivation and normal wakefulness conditions.

8. Modification of surface negative slow potential (CNV) in the human brain after total sleep loss.

9. Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas.

10. Amphetamine: differentiation by d and l isomers of behavior involving brain norepinephrine or dopamine.

1. Cocaine effects in sleep-deprived humans.

2. Effect of sleep deprivation on dopamine receptor function in normal subjects.