Literature DB >> 4086920

Quantitation of the granuloma fraction in leprosy skin biopsies by planimetry.

I A Cree, A C McDougall, G Coghill, J S Beck.   

Abstract

The proportion of the dermis occupied by granuloma in histological sections of skin biopsies from leprosy patients is known as the granuloma fraction. It can be estimated by direct microscopy on a scale of tenths using a low-power objective. We have compared this method with measurement of the granuloma fraction by planimetry, which gives comparable results but is much more accurate and precise. The implications of these findings for the objective assessment of the effects of treatment regimes on leprosy are discussed.

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Year:  1985        PMID： 4086920

Source DB:  PubMed          Journal:  Int J Lepr Other Mycobact Dis        ISSN： 0148-916X


  7 in total

1.  Measurements of blood flow and histometry of the cellular infiltrate in tuberculin skin test responses of the typical Koch type and the non-turgid variant form (Listeria-type) in pulmonary tuberculosis patients and apparently healthy controls.

Authors:  R C Potts; J S Beck; J H Gibbs; J M Grange; T Kardjito; J L Stanford
Journal:  Int J Exp Pathol       Date:  1992-10       Impact factor: 1.925

2.  Mast cells in leprosy skin lesions.

Authors:  I A Cree; G Coghill; J Swanson Beck
Journal:  J Clin Pathol       Date:  1990-03       Impact factor: 3.411

3.  Vascular endothelial growth factor is elevated in ocular fluids of eyes harbouring uveal melanoma: identification of a potential therapeutic window.

Authors:  S R Boyd; D Tan; C Bunce; A Gittos; M H Neale; J L Hungerford; S Charnock-Jones; I A Cree
Journal:  Br J Ophthalmol       Date:  2002-04       Impact factor: 4.638

4.  Uveal melanomas express vascular endothelial growth factor and basic fibroblast growth factor and support endothelial cell growth.

Authors:  S R Boyd; D S W Tan; L de Souza; M H Neale; N E Myatt; R A Alexander; M Robb; J L Hungerford; I A Cree
Journal:  Br J Ophthalmol       Date:  2002-04       Impact factor: 4.638

5.  Cell death in granulomata: the role of apoptosis.

Authors:  I A Cree; S Nurbhai; G Milne; J S Beck
Journal:  J Clin Pathol       Date:  1987-11       Impact factor: 3.411

6.  Diversity in migration of CD4 and CD8 lymphocytes in different microanatomical compartments of the skin in the tuberculin reaction in man.

Authors:  J S Beck; S M Morley; J G Lowe; R A Brown; J M Grange; J H Gibbs; R C Potts; T Kardjito
Journal:  Br J Exp Pathol       Date:  1988-12

7.  Clinical and Histopathological Response to Multidrug Therapy in Paucibacillary Leprosy at the end of 6 Months: A Prospective Observational Study from Eastern India.

Authors:  Indrashis Podder; Abanti Saha; Debabrata Bandyopadhyay
Journal:  Indian J Dermatol       Date:  2018 Jan-Feb       Impact factor: 1.494
  7 in total

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