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Literature DB >> 4084483

Stimulation of dopamine receptors (type 2) lowers human intraocular pressure.

Abstract

The interaction between bromocriptine and metoclopramide on intraocular pressure (IOP), pupil diameter, and other parameters were studied in healthy volunteers. Pupil diameter was not affected by both treatments and only bromocriptine lowered IOP. Prior treatment with metoclopramide blocked the IOP-lowering effect of bromocriptine. It is concluded that bromocriptine lowers IOP by stimulation of dopamine-2 receptors.

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Year: 1985 PMID： 4084483 PMCID： PMC1040880 DOI： 10.1136/bjo.69.12.909

Source DB: PubMed Journal: Br J Ophthalmol ISSN： 0007-1161 Impact factor: 4.638

7 in total

1. A new tonometer system.

Authors: B Grolman
Journal: Am J Optom Arch Am Acad Optom Date: 1972-08

2. Bromocriptine eyedrops lower intraocular pressure without affecting prolactin levels.

Authors: Q A Mekki; S J Warrington; P Turner
Journal: Lancet Date: 1984-02-04 Impact factor: 79.321

3. A behavioural and biochemical comparison of dopamine receptor blockade produced by haloperidol with that produced by substituted benzamide drugs.

Authors: P Jenner; A Clow; C Reavill; A Theodorou; C D Marsden
Journal: Life Sci Date: 1978-08-14 Impact factor: 5.037

4. A noninvasive tonometer in the measurement of the effects of pindolol and timolol on intraocular pressure in normal subjects.

Authors: S Rowley; J E Staunton; A Tosch; J H Stewart-Jones; D F Edgar; P Turner
Journal: Br J Ophthalmol Date: 1981-08 Impact factor: 4.638

5. Bromocriptine lowers intraocular pressure without affecting blood pressure.

Authors: Q A Mekki; S M Hassan; P Turner
Journal: Lancet Date: 1983-06-04 Impact factor: 79.321

6. Alpha-adrenolytic properties of bromocriptine in dogs.

Authors: J L Montastruc; P Montastruc
Journal: Arch Int Pharmacodyn Ther Date: 1982-11

Review 7. Metoclopramide. An updated review of its pharmacological properties and clinical use.

Authors: R A Harrington; C W Hamilton; R N Brogden; J A Linkewich; J A Romankiewicz; R C Heel
Journal: Drugs Date: 1983-05 Impact factor: 9.546

7 in total

11 in total

1. The effects of dopamine, haloperidol and bromocriptine on intraocular pressure.

Authors: O Elibol; C Güler; N Yüksel
Journal: Int Ophthalmol Date: 1992-09 Impact factor: 2.031

2. Effects of dopamine D-1 and D-2 receptors on intraocular pressure in conscious rabbits.

Authors: C Prünte; I Nuttli; R Markstein; C Kohler
Journal: J Neural Transm (Vienna) Date: 1997 Impact factor: 3.575

3. A comparison of the ocular hypotensive effect of 0.025% bromocriptine and 0.25% timolol eye drops in normal human volunteers.

Authors: M R al-Sereiti; R L Coakes; D P O'Sullivan; P Turner
Journal: Br J Clin Pharmacol Date: 1989-10 Impact factor: 4.335

4. The effect of a single oral dose of pergolide on intraocular pressure and pupil diameter.

Authors: M R al-Sereiti; R F Quik; P Turner
Journal: Br J Clin Pharmacol Date: 1989-09 Impact factor: 4.335

5. The effects of lisuride, terguride and bromocriptine on intraocular pressure (IOP).

Authors: M R Al-Sereiti; P Turner
Journal: Br J Clin Pharmacol Date: 1989-02 Impact factor: 4.335

6. Bromocriptine, dopamine and glaucoma.

Authors: P Turner
Journal: Postgrad Med J Date: 1986-09 Impact factor: 2.401

7. A preliminary study of the ocular hypotensive effects of bromocriptine in diabetic patients with autonomic neuropathy.

Authors: M R al-Sereiti; P Turner; E A Gale
Journal: Postgrad Med J Date: 1991-04 Impact factor: 2.401