Literature DB >> 408435

Strucutres of the capsular polysaccharides of Neisseria meningitidis as determined by 13C-nuclear magnetic resonance spectroscopy.

H J Jennings, A K Bhattacharjee, D R Bundle, C P Kenny, A Martin, I C Smith.   

Abstract

The application of 13C-nuclear magnetic resonance spectroscopy to the structural determination of the capsular polysaccharide antigens of Neisseria meningitidis is described. Complete assignments of the spectra of the polysaccharides of serogroups A, B, C, W-135, X and Y were made and were based mainly on previous assignments made for the monomer units of the respective polysaccharides. This technique provides information on all structural aspects of the polysaccharides including composition, mode of linkage, location of O-acetyl substituents, sequence, and conformation. In addition, nuclear magnetic resonance is nondestructive, extremely rapid, and has enormous potential in bacteriological research.

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Year:  1977        PMID： 408435     DOI： 10.1093/infdis/136.supplement.s78

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  20 in total

1.  Serogroup-specific interaction of Neisseria meningitidis capsular polysaccharide with host cell microtubules and effects on tubulin polymerization.

Authors:  Adelfia Talà; Laura Cogli; Mario De Stefano; Marcella Cammarota; Maria Rita Spinosa; Cecilia Bucci; Pietro Alifano
Journal:  Infect Immun       Date:  2013-10-28       Impact factor: 3.441

Review 2.  Prospects for vaccine prevention of meningococcal infection.

Authors:  Lee H Harrison
Journal:  Clin Microbiol Rev       Date:  2006-01       Impact factor: 26.132

3.  O acetylation of the enterobacterial common antigen polysaccharide is catalyzed by the product of the yiaH gene of Escherichia coli K-12.

Authors:  Junko Kajimura; Arifur Rahman; James Hsu; Matthew R Evans; Kevin H Gardner; Paul D Rick
Journal:  J Bacteriol       Date:  2006-08-25       Impact factor: 3.490

4.  Protective meningococcal capsular polysaccharide epitopes and the role of O acetylation.

Authors:  Peter C Fusco; Esmé K Farley; Chun-Hsien Huang; Samuel Moore; Francis Michon
Journal:  Clin Vaccine Immunol       Date:  2007-03-21

5.  Meningococcal polysaccharide A O-acetylation levels do not impact the immunogenicity of the quadrivalent meningococcal tetanus toxoid conjugate vaccine: results from a randomized, controlled phase III study of healthy adults aged 18 to 25 years.

Authors:  Socorro Lupisan; Kriengsak Limkittikul; Nestor Sosa; Pornthep Chanthavanich; Véronique Bianco; Yaela Baine; Marie Van der Wielen; Jacqueline M Miller
Journal:  Clin Vaccine Immunol       Date:  2013-07-24

6.  Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A.

Authors:  Nicholas K Hurlburt; Jasper Guan; Hoonsan Ong; Hai Yu; Xi Chen; Andrew J Fisher
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2020-10-29       Impact factor: 1.056

7.  Neuraminidase associated with coliphage E that specifically depolymerizes the Escherichia coli K1 capsular polysaccharide.

Authors:  S Tomlinson; P W Taylor
Journal:  J Virol       Date:  1985-08       Impact factor: 5.103

8.  Purification and characterization of polyphosphate kinase from Neisseria meningitidis.

Authors:  C R Tinsley; B N Manjula; E C Gotschlich
Journal:  Infect Immun       Date:  1993-09       Impact factor: 3.441

Review 9.  Meningococcal A, C, Y and W-135 polysaccharide-protein conjugate vaccines.

Authors:  David Pace; Andrew J Pollard
Journal:  Arch Dis Child       Date:  2007-10       Impact factor: 3.791

10.  Group C Neisseria meningitidis variant polysaccharide vaccines in children.

Authors:  M C Steinhoff; E B Lewin; E C Gotschlich; J B Robbins
Journal:  Infect Immun       Date:  1981-10       Impact factor: 3.441
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