Literature DB >> 4084288

Primary structure of bovine brain acidic fibroblast growth factor (FGF).

F Esch, N Ueno, A Baird, F Hill, L Denoroy, N Ling, D Gospodarowicz, R Guillemin.   

Abstract

The major anionic mitogenic polypeptide for endothelial cells, acidic fibroblast growth factor (FGF), has been purified to homogeneity from bovine brain and its complete primary structure established by gas-phase sequence analysis. The 140 amino acid (Mr 16,000) protein has been previously shown to be a potent growth factor for many diverse cell types of mesodermal origin, in vitro, and an angiogenic agent, in vivo. The amino acid sequence of bovine brain acidic FGF has a 53% absolute homology with that of bovine pituitary basic FGF suggesting that these endothelial cell mitogens are derived from a single ancestral gene.

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Year:  1985        PMID： 4084288     DOI： 10.1016/0006-291x(85)90942-8

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  26 in total

1.  Basic fibroblast growth factor as a growth inhibitor for cultured human tumor cells.

Authors:  L Schweigerer; G Neufeld; D Gospodarowicz
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

2.  Basic fibroblast growth factor induces angiogenesis in vitro.

Authors:  R Montesano; J D Vassalli; A Baird; R Guillemin; L Orci
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

Review 3.  [Osteoinduction and -reparation].

Authors:  N R Kübler
Journal:  Mund Kiefer Gesichtschir       Date:  1997-02

4.  Multiple forms of basic fibroblast growth factor: amino-terminal cleavages by tumor cell- and brain cell-derived acid proteinases.

Authors:  M Klagsbrun; S Smith; R Sullivan; Y Shing; S Davidson; J A Smith; J Sasse
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

Review 5.  Angiogenic growth factors in myocardial infarction: a critical appraisal.

Authors:  Hemalatha Thiagarajan; UmaMaheswari Thiyagamoorthy; Iswariya Shanmugham; Gunadharini Dharmalingam Nandagopal; Anbukkarasi Kaliyaperumal
Journal:  Heart Fail Rev       Date:  2017-11       Impact factor: 4.214

6.  Heparin-like glycosaminoglycans influence growth and phenotype of human arterial smooth muscle cells in vitro. II. The platelet-derived growth factor A-chain contains a sequence that specifically binds heparin.

Authors:  G Fager; G Camejo; U Olsson; G Ostergren-Lundén; G Bondjers
Journal:  In Vitro Cell Dev Biol       Date:  1992-03

7.  Embryonic chick muscle produces an FGF-like activity.

Authors:  D S Morris; S J Stock; J C McLachlan
Journal:  Experientia       Date:  1996-08-15

8.  Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor.

Authors:  W H Burgess; T Mehlman; D R Marshak; B A Fraser; T Maciag
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

9.  Effects of endothelial cell growth factor on bone remodelling in vitro.

Authors:  E Canalis; J Lorenzo; W H Burgess; T Maciag
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

10.  Receptor- and heparin-binding domains of basic fibroblast growth factor.

Authors:  A Baird; D Schubert; N Ling; R Guillemin
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205
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