Literature DB >> 4084192

The prolonged effects of naloxone on play behavior and feeding in the rat.

M A Siegel, R A Jensen, J Panksepp.   

Abstract

The effects of naloxone on social play and feeding behaviors of postweanling and adult Long-Evans hooded rats were studied. Administration of 1.0, 5.0, or 10.0 mg/kg naloxone reduced play in a dose-related fashion. The effects of a 5.0-mg/kg dose of naloxone could be detected at least 3 h after administration, in terms of both a decrease in social behavior and decreased food consumption, indicating that the behavioral time course of naloxone effects is greater than some reports in the pharmacokinetic literature suggest.

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Year:  1985        PMID： 4084192     DOI： 10.1016/s0163-1047(85)91024-6

Source DB:  PubMed          Journal:  Behav Neural Biol        ISSN： 0163-1047


  10 in total

1.  Cannabinoid and opioid modulation of social play behavior in adolescent rats: differential behavioral mechanisms.

Authors:  Viviana Trezza; Louk J M J Vanderschuren
Journal:  Eur Neuropsychopharmacol       Date:  2008-04-22       Impact factor: 4.600

Review 2.  The neurobiology of social play and its rewarding value in rats.

Authors:  Louk J M J Vanderschuren; E J Marijke Achterberg; Viviana Trezza
Journal:  Neurosci Biobehav Rev       Date:  2016-08-29       Impact factor: 8.989

3.  Nicotine-induced plasma corticosterone is attenuated by social interactions in male and female adolescent rats.

Authors:  N S Pentkowski; M R Painter; K J Thiel; N A Peartree; T H C Cheung; P Deviche; M Adams; J Alba; J L Neisewander
Journal:  Pharmacol Biochem Behav       Date:  2011-07-18       Impact factor: 3.533

4.  It still hurts: altered endogenous opioid activity in the brain during social rejection and acceptance in major depressive disorder.

Authors:  D T Hsu; B J Sanford; K K Meyers; T M Love; K E Hazlett; S J Walker; B J Mickey; R A Koeppe; S A Langenecker; J-K Zubieta
Journal:  Mol Psychiatry       Date:  2015-01-20       Impact factor: 15.992

5.  Nucleus accumbens μ-opioid receptors mediate social reward.

Authors:  Viviana Trezza; Ruth Damsteegt; E J Marijke Achterberg; Louk J M J Vanderschuren
Journal:  J Neurosci       Date:  2011-04-27       Impact factor: 6.167

6.  Validation of a novel social investigation task that may dissociate social motivation from exploratory activity.

Authors:  Terrence Deak; Hiroyuki Arakawa; Marni Y V Bekkedal; Jaak Panksepp
Journal:  Behav Brain Res       Date:  2008-12-14       Impact factor: 3.332

7.  Ethanol-induced social facilitation in adolescent rats: role of endogenous activity at mu opioid receptors.

Authors:  Elena I Varlinskaya; Linda P Spear
Journal:  Alcohol Clin Exp Res       Date:  2009-03-19       Impact factor: 3.455

8.  Response of the μ-opioid system to social rejection and acceptance.

Authors:  D T Hsu; B J Sanford; K K Meyers; T M Love; K E Hazlett; H Wang; L Ni; S J Walker; B J Mickey; S T Korycinski; R A Koeppe; J K Crocker; S A Langenecker; J-K Zubieta
Journal:  Mol Psychiatry       Date:  2013-08-20       Impact factor: 15.992

Review 9.  State-dependent μ-opioid modulation of social motivation.

Authors:  Guro E Loseth; Dan-Mikael Ellingsen; Siri Leknes
Journal:  Front Behav Neurosci       Date:  2014-12-12       Impact factor: 3.558

10.  Effects of opioid receptor stimulation and blockade on touch pleasantness: a double-blind randomised trial.

Authors:  Guro E Løseth; Marie Eikemo; Siri Leknes
Journal:  Soc Cogn Affect Neurosci       Date:  2019-05-17       Impact factor: 3.436
  10 in total

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