Literature DB >> 4083280

Evidence for the close linkage between lymphocyte cytosol polypeptide with molecular weight of 64,000 (LCP1) and esterase D.

I Kondo, H Hamaguchi.   

Abstract

The genetic linkage of the loci for lymphocyte cytosol polypeptide with molecular weight of 64,000 (LCP1) and esterase (ESD) were examined by two-dimensional gel electrophoresis using blood from four informative families. No recombinants were observed in the four families totaling 17 children, giving a summed lod score of 4.221 at recombination fraction 0. This result indicates that the gene for LCP1 is closely linked to the ESD locus, which is assigned to the chromosomal region 13q14.11. This finding also suggests that the LCP1 locus is linked to the retinoblastoma gene, which is assigned to the same chromosomal region and closely linked to the ESD locus.

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Year:  1985        PMID： 4083280      PMCID： PMC1684732     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  19 in total

1.  Sequential tests for the detection of linkage.

Authors:  N E MORTON
Journal:  Am J Hum Genet       Date:  1955-09       Impact factor: 11.025

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  High resolution two-dimensional electrophoresis of proteins.

Authors:  P H O'Farrell
Journal:  J Biol Chem       Date:  1975-05-25       Impact factor: 5.157

4.  Ultrasensitive stain for proteins in polyacrylamide gels shows regional variation in cerebrospinal fluid proteins.

Authors:  C R Merril; D Goldman; S A Sedman; M H Ebert
Journal:  Science       Date:  1981-03-27       Impact factor: 47.728

5.  Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis: V. Genetic polymorphism of cytosol 31k polypeptide.

Authors:  I Kondo; K Yamakawa; M Shibasaki; T Yamamoto; H Hamaguchi
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

6.  Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis: 2. Genetic polymorphism of lymphocyte cytosol 64K polypeptide.

Authors:  H Hamaguchi; M Yamada; A Noguchi; K Fujii; M Shibasaki; R Mukai; T Yabe; I Kondo
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

7.  Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14.

Authors:  R S Sparkes; M C Sparkes; M G Wilson; J W Towner; W Benedict; A L Murphree; J J Yunis
Journal:  Science       Date:  1980-05-30       Impact factor: 47.728

8.  Location of the retinoblastoma susceptibility gene(s) and the human esterase D locus.

Authors:  P Ward; S Packman; W Loughman; M Sparkes; R Sparkes; A McMahon; T Gregory; A Ablin
Journal:  J Med Genet       Date:  1984-04       Impact factor: 6.318

9.  Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis: VI. Identification of esterase D in the two-dimensional gel electrophoresis pattern of cellular proteins.

Authors:  I Kondo; T Yamamoto; K Yamakawa; S Harada; H Oishi; I Nishigaki; H Hamaguchi
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

10.  Retinoblastoma-del(13q14): report of two patients, one with a trisomic sib due to maternal insertion. Gene-dosage effect for esterase D.

Authors:  H Rivera; C Turleau; J de Grouchy; C Junien; S Despoisse; J M Zucker
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132
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  4 in total

1.  Error detected in published lod scores.

Authors:  J L Haines
Journal:  Am J Hum Genet       Date:  1986-10       Impact factor: 11.025

2.  A case report of a patient with retinoblastoma and chromosome 13q deletion: assignment of a new gene (gene for LCP1) on human chromosome 13.

Authors:  I Kondo; K Shin; S Honmura; H Nakajima; E Yamamura; H Satoh; M Terauchi; Y Usuki; H Takita; H Hamaguchi
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

3.  Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts.

Authors:  C S Lin; R H Aebersold; S B Kent; M Varma; J Leavitt
Journal:  Mol Cell Biol       Date:  1988-11       Impact factor: 4.272

4.  Genetic analysis of human lymphocyte proteins by two-dimensional gel electrophoresis. VIII. Genetic polymorphism of cytosol polypeptide with molecular weight of 20,000.

Authors:  I Kondo; S Harada; M Shibasaki; K Yamakawa; T Yamamoto; H Hamaguchi
Journal:  Hum Genet       Date:  1986-04       Impact factor: 4.132
  4 in total

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