| Literature DB >> 408180 |
H J Hess, J S Bindra, J W Constantine, W Elger, O Loge, E Schillinger, W Losert.
Abstract
N-methanesulfonyl 16-phenoxy-omega-tetranor PGE2 is a prostaglandin analog which is markedly more tissue selective than PGE2. This compound is 10-30 times more potent than PGE2 in animal models which are considered relevant to antifertility effects in humans. In pharmacological tests which are believed to be predictive for side effects in humans, the compound has potency either equal to or less than that of PGE2.Entities:
Mesh：
Substances：
Year: 1977 PMID： 408180 DOI： 10.1007/bf01945979
Source DB: PubMed Journal: Experientia ISSN： 0014-4754