Literature DB >> 4079445

An all-glass perfusator for investigation of the intestinal transport and metabolism of foreign compounds in vitro.

E Richter, G J Strugala.   

Abstract

The in vitro perfusion technique of surviving intestinal segments as described by Fisher and Parsons (1949) and modified by Rummel and Stupp (1960) was further improved by the introduction of an all-glass perfusator for studying the intestinal transport and metabolism of lipophilic xenobiotics.

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Year:  1985        PMID: 4079445     DOI: 10.1016/0160-5402(85)90005-1

Source DB:  PubMed          Journal:  J Pharmacol Methods        ISSN: 0160-5402


  2 in total

1.  Independence of in vitro iron absorption from mucosal transferrin content in rat jejunal and ileal segments.

Authors:  K Schümann; K Osterloh; W Forth
Journal:  Blut       Date:  1986-11

Review 2.  Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.

Authors:  Sheila Annie Peters; Christopher R Jones; Anna-Lena Ungell; Oliver J D Hatley
Journal:  Clin Pharmacokinet       Date:  2016-06       Impact factor: 6.447

  2 in total

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