Literature DB >> 4078496

A model of a myelinated nerve axon: threshold behaviour and propagation.

P Grindrod, B D Sleeman.   

Abstract

A model of a myelinated nerve axon is developed on the basis of FitzHugh-Nagumo dynamics under the assumption that the nodes of Ranvier are of small but finite width. It is shown that a periodic excited state may not exist if the width of the nodes is too small and the leakage across the myelin sheath is too great. The propagation of a super threshold pulse is prevented in the absence of nodes. Global stability of the resting equilibrium state is investigated as well as the propagation of "wave front", type solutions.

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Year:  1985        PMID: 4078496     DOI: 10.1007/BF00276561

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  1 in total

1.  Threshold conditions for a diffusive model of a myelinated axon.

Authors:  J Bell; C Cosner
Journal:  J Math Biol       Date:  1983       Impact factor: 2.259

  1 in total

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