Literature DB >> 4077074

Survival after massive ingestion of carbon tetrachloride treated by intravenous infusion of acetylcysteine.

P W Mathieson, G Williams, J E MacSweeney.   

Abstract

A 61-year-old man ingested a large amount of carbon tetrachloride, well in excess of the adult lethal dose. The level of the compound was assayed in his blood and the levels were the highest ever recorded by the Guy's Hospital Poisons Unit. He was treated by intravenous infusion of acetylcysteine and survived with relatively mild clinical and biochemical evidence of toxicity. Possible reasons for his survival are discussed, as are the implications for the management of future cases.

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Year:  1985        PMID: 4077074     DOI: 10.1177/096032718500400610

Source DB:  PubMed          Journal:  Hum Toxicol        ISSN: 0144-5952


  6 in total

1.  The biosynthesis of taurine fromN-acetyl-L-cysteine and other precursorsin vivo and in rat hepatocytes.

Authors:  C J Waterfield; J A Timbrell
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

2.  Diagnosis of chlorinated hydrocarbon poisoning by x ray examination.

Authors:  S Dally; R Garnier; C Bismuth
Journal:  Br J Ind Med       Date:  1987-06

3.  The role of acetylcysteine in clinical toxicology.

Authors:  R J Flanagan
Journal:  Med Toxicol       Date:  1987 Mar-Apr

Review 4.  Utility of acetylcysteine in treating poisonings and adverse drug reactions.

Authors:  P A Chyka; A Y Butler; B J Holliman; M I Herman
Journal:  Drug Saf       Date:  2000-02       Impact factor: 5.606

Review 5.  Hyperbaric oxygen treatment for carbon tetrachloride poisoning.

Authors:  K K Burkhart; A H Hall; R Gerace; B H Rumack
Journal:  Drug Saf       Date:  1991 Sep-Oct       Impact factor: 5.606

6.  N-acetylcysteine attenuates alcohol-induced oxidative stress in the rat.

Authors:  Resat Ozaras; Veysel Tahan; Seval Aydin; Hafize Uzun; Safiye Kaya; Hakan Senturk
Journal:  World J Gastroenterol       Date:  2003-01       Impact factor: 5.742

  6 in total

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