| Literature DB >> 4074642 |
R P Gallagher, J M Elwood, G B Hill, A J Coldman, W J Threlfall, J J Spinelli.
Abstract
A study of 361 female melanoma patients and age matched controls was conducted in the four western provinces of Canada. Analysis of reproductive factors showed a significant negative association between number of livebirths and risk of melanoma. The relationship persisted for superficial spreading melanomas after adjustment for host pigmentation factors, freckling, and educational status. An inverse association between bilateral oophorectomy and risk of superficial spreading melanoma was also seen. No association was found between risk of melanoma and age at first birth, age at menarche and age at natural menopause. No association was found between risk of superficial spreading or nodular melanoma and use of either oral contraceptives or menopausal oestrogens.Entities:
Keywords: Age Factors; Americas; Anthropometry; Biology; Body Weight; Canada; Cancer; Comparative Studies; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Methods--side effects; Control Groups; Dermatological Effects--etiology; Developed Countries; Developing Countries; Diseases; Educational Status; Endocrine System; Estrogens--side effects; Family Planning; Fertility Measurements; Hormones; Marital Status; Maternal Age; Measurement; Menarche; Menopause; Menstruation; Neoplasms; North America; Northern America; Nuptiality; Oral Contraceptives--side effects; Parental Age; Parity; Physiology; Population; Population At Risk; Population Characteristics; Reproduction; Reproductive Control Agents; Research Methodology; Studies
Mesh：
Substances：
Year: 1985 PMID： 4074642 PMCID： PMC1977278 DOI： 10.1038/bjc.1985.275
Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640