| Literature DB >> 4074621 |
P G Blain, J C Mucklow, M D Rawlins, D F Roberts, P A Routledge, D G Shand.
Abstract
The concentration of alpha 1-acid glycoprotein (AAG) was measured in plasma from 200 healthy subjects belonging to 78 family units. The AAG concentration varied markedly between individuals (mean 0.77, range 0.36-1.46 g 1(-1]. When the genetic contribution to the variability was assessed, the only significant correlation observed was that between husband and wife and this was weak. We conclude that in addition to the known effects of age and gender, environmental (rather than genetic) factors largely determine the variance of AAG concentrations.Mesh:
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Year: 1985 PMID: 4074621 PMCID: PMC1400715 DOI: 10.1111/j.1365-2125.1985.tb05107.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN: 0306-5251 Impact factor: 4.335