| Literature DB >> 4071471 |
Abstract
The effect of calcium dobesilate (calcium dihydroxy-2,5 benzenesulphonate) on thrombus formation in vivo was evaluated. Experimental thrombi were induced in a venule of a hamster cheek pouch following iontophoresis of adenosine diphosphate (ADP). Calcium dobesilate administered intraperitoneally as a single injection inhibited thrombus formation in a time- and dose-dependent manner. Furthermore, the combination of calcium dobesilate and aspirin resulted in the potentiation of the inhibition of thrombus formation.Entities:
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Year: 1985 PMID： 4071471 DOI： 10.1016/0049-3848(85)90332-9
Source DB: PubMed Journal: Thromb Res ISSN： 0049-3848 Impact factor: 3.944