| Literature DB >> 4069376 |
Abstract
Neuropathologic examination of two patients with dementia showed chronic bilateral medial temporal lobe ischemic damage that included the hippocampus (particularly the CA-1 region), subiculum, and amygdala. Both patients had several myocardial infarctions, and the relatively circumscribed cerebral injury may have resulted from one or more episodes of global hypoxic ischemia. Focal hippocampal injury has been associated with amnesia. The additional damage to medial temporal lobe structures may have caused the dementia.Entities:
Mesh:
Year: 1985 PMID: 4069376 DOI: 10.1212/wnl.35.12.1793
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910