| Literature DB >> 4067846 |
Abstract
We describe an approach to zero-order drug delivery systems that utilizes a device consisting of multiple holes uniformly distributed in an impermeable membrane. The interior of the device is filled with a suspension of a drug in a polymeric matrix. Near zero-order release is attained by using the proper density and configuration of holes on the surface of the device.Mesh：
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Year: 1985 PMID： 4067846 DOI： 10.1002/jps.2600740904
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534