Literature DB >> 4067316

The influence of hapten density on the assay of penicilloylated proteins in fluids.

D Lee, J M Dewdney, R G Edwards.   

Abstract

The use of inhibition radioimmunoassays for the measurement of penicilloylated proteins in biological fluids is compromised by the dominant influence of hapten density. Precise quantitation, and therefore assessment of antigenicity and immunogenicity, cannot be achieved in the absence of knowledge of the number and distribution of haptenic groups on the protein carrier. These assays may not, therefore, be appropriate for the measurement of potential allergenic residues in food products.

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Year:  1985        PMID: 4067316     DOI: 10.1016/0022-1759(85)90430-2

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  3 in total

1.  Determination of IgE antibodies to the benzylpenicilloyl determinant: a comparison of the sensitivity and specificity of three radio allergo sorbent test methods.

Authors:  J J Garcia; M Blanca; F Moreno; J M Vega; C Mayorga; J Fernandez; C Juarez; A Romano; E de Ramon
Journal:  J Clin Lab Anal       Date:  1997       Impact factor: 2.352

2.  Fixation of penicilloyl groups to albumin and appearance of anti-penicilloyl antibodies in penicillin-treated patients.

Authors:  P Lafaye; C Lapresle
Journal:  J Clin Invest       Date:  1988-07       Impact factor: 14.808

3.  The influence of the carrier molecule on amoxicillin recognition by specific IgE in patients with immediate hypersensitivity reactions to betalactams.

Authors:  Adriana Ariza; Cristobalina Mayorga; María Salas; Inmaculada Doña; Ángela Martín-Serrano; Ezequiel Pérez-Inestrosa; Dolores Pérez-Sala; Antonio E Guzmán; María I Montañez; María J Torres
Journal:  Sci Rep       Date:  2016-10-12       Impact factor: 4.379

  3 in total

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