| Literature DB >> 4066504 |
K Dornberger, R Hübener, W Ihn, H Thrum, L Radics.
Abstract
By using a strain of Streptomyces willmorii, daunorubicin (daunomycin) was stereoselectively converted into N-acetyl-13(S)-dihydrodaunomycin and bisanhydro-13-dihydrodaunomycinone. The absolute stereochemistry of the new chiral center in N-acetyl-13(S)-dihydrodaunomycin was established by means of nuclear Overhauser effect measured in the 9,13-O-isopropylidene derivative.Entities:
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Year: 1985 PMID： 4066504 DOI： 10.7164/antibiotics.38.1219
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649