Literature DB >> 4066319

[Hypotrichosis congenita hereditaria Maria Unna].

G Wirth, I Bindewald, W Küster, G Goerz.   

Abstract

A mother and child are reported, who suffer from hypotrichosis of the Marie-Unna type. At birth they had little or no hair. Subsequently, coarse and wirelike hair grew during early childhood, followed later by alopecia. Examination of the hair using scanning electron microscopy showed peeling of the cuticle and longitudinal ridging. Protein analysis showed no abnormalities compared with normal hair, but there were similarities with the so-called uncombable hair syndrome.

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Year:  1985        PMID: 4066319

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  1 in total

1.  The gene for hypotrichosis of Marie Unna maps between D8S258 and D8S298: exclusion of the hr gene by cDNA and genomic sequencing.

Authors:  M van Steensel; F J Smith; P M Steijlen; I Kluijt; H P Stevens; A Messenger; H Kremer; M G Dunnill; C Kennedy; C S Munro; V R Doherty; J A McGrath; S P Covello; C M Coleman; J Uitto; W H McLean
Journal:  Am J Hum Genet       Date:  1999-08       Impact factor: 11.025

  1 in total

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