Literature DB >> 406630

An automated method for studying exploratory and stereotyped behaviour in rats.

R O Makanjuola, G Hill, I Maben, R C Dow, G W Ashcroft.   

Abstract

A technique is described for studying exploratory as well as stereotyped behaviour in rats using an automated hole-board. Both visual and automated recordings can be employed using the technique. Hole dipping is monitored automatically using an infra-red detector system. Repetitive patterns of hole-dipping are used as parameters of stereotyped behaviour while the more random patterns of hole-dipping are used as parameters of exploration. There was a high significant correlation between the records of hole-dipping behaviour as recorded visually and automatically. There was also a high significant correlation between the measures of repetitiveness/randomness of hole-dipping behaviour from automatic and visual recordings. The pattern and levels of hole-dipping conformed with expectations both as regards changes with time and with increasing doses of dl-amphetamine.

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Year:  1977        PMID: 406630     DOI: 10.1007/bf00426711

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  33 in total

1.  Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone. IV. Influence of haloperidol (R 1625) and of chlorpromazine on the behaviour of rats in an unfamiliar "open field" situation.

Authors:  P A JANSSEN; A H JAGENEAU; K H SCHELLEKENS
Journal:  Psychopharmacologia       Date:  1960-09-13

2.  Effect of drugs on emotional behaviour in rats.

Authors:  R W RYALL
Journal:  Nature       Date:  1958-12-06       Impact factor: 49.962

3.  The effect of activity deprivation upon exploratory behavior.

Authors:  K C MONTGOMERY
Journal:  J Comp Physiol Psychol       Date:  1953-12

4.  The role of the raphé and extrapyramidal nuclei in the stereotyped and circling responses to quipazine.

Authors:  B Costall; R J Naylor
Journal:  J Pharm Pharmacol       Date:  1975-05       Impact factor: 3.765

5.  Effects of psychotropic drugs on emotional behavior: exploratory behavior of naive rats in holed open field.

Authors:  M Nakama; T Ochiai; Y Kowa
Journal:  Jpn J Pharmacol       Date:  1972-12

6.  A dissociation of the effects of d-amphetamine on locomotor activity and exploration in rats.

Authors:  T Robbins; S D Iversen
Journal:  Psychopharmacologia       Date:  1973-01-01

7.  Methylphenidate induced inhibition of exploratory behaviour in rats.

Authors:  R N Hughes
Journal:  Life Sci I       Date:  1972-02-15

8.  Effects of psychotropic agents on the exploratory behavior of rats in a Y-shaped box.

Authors:  H Ito; S Takaori
Journal:  Jpn J Pharmacol       Date:  1968-09

9.  Effects of habituation to fear on the exploratory behavior of rats.

Authors:  D Lester
Journal:  Nature       Date:  1968-11-30       Impact factor: 49.962

10.  Drug effects on exploration of a combined maze and open-field system by rats.

Authors:  K Bättig
Journal:  Ann N Y Acad Sci       Date:  1969-07-30       Impact factor: 5.691

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  15 in total

1.  The time and space machine: continuous measurement of drug-induced behavior patterns in the rat.

Authors:  D M Stoff; K Stauderman; R J Wyatt
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

2.  An automated method for studying stereotyped gnawing.

Authors:  D E Moss; S B McMaster; E Castañeda; R L Johnson
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

3.  Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate.

Authors:  Fumitoshi Irie; Hedieh Badie-Mahdavi; Yu Yamaguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-12       Impact factor: 11.205

4.  Sources of variation in locomotor activity and stereotypy in rats treated with d-amphetamine.

Authors:  L Mumford; A R Teixeira; R Kumar
Journal:  Psychopharmacology (Berl)       Date:  1979-04-25       Impact factor: 4.530

5.  The effects of psychotropic drugs on exploratory and stereotyped behaviour of rats studied on a hole-board.

Authors:  R O Makanjuola; G Hill; R C Dow; G Campbell; G W Ashcroft
Journal:  Psychopharmacology (Berl)       Date:  1977-11-24       Impact factor: 4.530

6.  Development of a mouse test for repetitive, restricted behaviors: relevance to autism.

Authors:  Sheryl S Moy; Jessica J Nadler; Michele D Poe; Randal J Nonneman; Nancy B Young; Beverly H Koller; Jacqueline N Crawley; Gary E Duncan; James W Bodfish
Journal:  Behav Brain Res       Date:  2007-11-04       Impact factor: 3.332

7.  Another look at amphetamine-induced stereotyped locomotor activity in rats using a new statistic to measure locomotor stereotypy.

Authors:  K Mueller; E M Hollingsworth; D R Cross
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

8.  Lithium induces dose-related increases and decreases in activity levels in the rat.

Authors:  P Cappeliez; N White
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

9.  Behavioural responses to stereotactically controlled injections of monoamine neurotransmitters into the accumbens and caudate-putamen nuclei.

Authors:  R O Makanjuola; R C Dow; G W Ashcroft
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

10.  The acute periventricular injury syndrome: a possible animal model for psychotic disease.

Authors:  J Kline; K H Reid
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

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